Patients with chronic kidney disease, especially in more advanced stages (eGFR less than 30 mL/min per 1·73 m²) often do not exhibit linear progression of disease, which might be related to superimposed episodes of acute kidney injury or other factors. Some studies suggest that each acute kidney injury event might accelerate progression of chronic kidney disease.
This is a companion discussion topic for the original article at https://patient.info/doctor/acute-on-chronic-kidney-disease