In people with migraine, it is thought that some chemicals in the brain increase in activity and as a result parts of the brain then send out confused signals which result in the symptoms of headache and sickness. Why people with migraine should develop these chemical changes is not clear, but for some people there may be things which trigger an attack, like certain foods or drinks.
This is a companion discussion topic for the original article at https://patient.info/medicine/almotriptan-for-migraine-2