I’ve been given promethazine antihistamine for sedation for sleep. Has any one else put on a lot of weight on this or any one know if antihistamine can cause weight gain. I was on mitrazapine n came off it because I piled on the weight too go on to venlafaxine but I can’t sleep it’s just a vicious circle 
Can’t say for promethazine per say…
However, when I have a bout of insomnia, I have an open script for Zopiclone, which works wonders for me. You may want to ask your physician about it.
It can be habit forming though and you need to take them only if needed.
mirtazapene is particularly bad for weight gain, but then others can cause it as well. Until your new anti depressant is fully working, and you are sleeping okay, then sleep and mental wellbeing are your priority. Once ven is working fully, you should be able to come off the anti histamine with few problems. i dont think weight gain is a priority for you at the moment, its something to address, when you are better. i can understand your worries. i put a lot of weight on, while on my previous ad seroxat. i lost loads of weight earlier this year, when i got into a complete state, when it stopped working. i couldnt eat anything. now recovering on ven, and my appetite is back as strong as ever, its a constant issue. however, ive decided theres no way im putting the weight back on. completely cut out all crap. no slip ups, all or nothing. a month or two of that, and it can break your cravings for unhealthy food. also, dont keep much food in your house, certainly no crap. its amazing how the cravings stop, when you have to go to the shop to get something you dont really need. this works really well. just keep the essentials in your home. hope some of this helps.
ps, i said just keep the essentials in your home. actually its a bit extreme, but i dont keep any food in my home. i shop daily for food i need for the day. its extreme, but it works. if i store food at home, i will eat it, so i make sure there isnt any.
How was coming off the mirt ?
Nigel the venlafaxine is working I’m not as ill as I was. It’s just the sleeping I’m having problems with. They should of known my back ground that they took me off mitrazapine because of the weight gain put me on venlafaxine and I’ve been fine apart from the sleeping. I am so glad I’m better I don’t want too sound ungrateful but I feel huge n uncomfortable 
Yeah they gave me that but would only give me it for a short time in case I got addicted. But I can’t sleep without the antihistamine so surely I could get addicted too them too x
Not good at all I’m suffering with insomnia now n before I had no problem sleeping 
Is it just insomnia or did you have other symptoms ?
Ven can cause weight gain. They say it dosen t but for some it does.
anxiety and therefore sleep, are normally the last thing that gets better. on the ssri forums, general consensus was that it took 3 months for people to be anxiety free, although there were a few that said it took 6 months. ven seems to take longer. how long have you been on ven? its your anxiety levels that cause the insomnia. are you completely caffeine free? with me, the weight gain started when seroxat stopped working so well, over a few years. i didnt care about much, and excessive eating was enjoyable. to lose weight its going to need your own will and discipline.they will improve when ven is fully working. late last year i just decided id had enough of being over weight, and lost a stone. then i got depressed, and lost a lot more. when ven started working in july, thats when my food cravings started again. cravings come and go. if you keep unhealthy food in your home, when you have cravings, its there, and you can easily satisfy yourself. if its not easily available, the craving goes away, when something distracts you. with me, if i start eating unhealthy stuff at home, i dont stop until its all gone. try not keeping unhealthy food at home, after a few weeks, you sort of get used to it. its still a struggle for me now, you want to choosing and buying your food when you feel good and are more disciplined. if you ban yourself from unhealthy food and drinks, it forces you to find healthier options.
Not going too lie I ended up in a bad way never slept for 3 weeks crying constantly n never ate for a week collapsed in the bathroom I should of got help sooner but I just thought I will manage it will get better but it didn’t and the crisis mental health team were called too my house I got better with their help. They said I tapered off mitrazapine too fast n should have done it over a longer time. I was off work for 4 weeks but I’m much better now on venlafaxine xx
I know what your saying I watch what I’m eating it’s like a lot of fluid I’m carrying feeling really bloated I eat really healthyhealthy x
Hi Karen, it’s been 2 weeks for me off Mirt. I started Sertraline alongside VEN . My sleep s all over the shop. I take either 0.25 xanax or 25 Sleepease from boots. I usually wake up around 2am and then I am awake for an hour and fall asleep eventully until 5. I get 5 hours sleep atm… I have also tinnitus on Ven that hasn’t gone yet so sleeping is a nightmare because of that… hell on EARTH… xx
What dose of mirt were you on and did you taper ?
I was on 30 then went down to 15 for one week and then 15 every other day then stopped. I had to taper quickly because I was due to start Sertraline. No side effects apart from insomnia but it could also be a side effect of Sert.
How long were you on 30 ?
I am tapering very slowely of 45 but i think i may be being over cautious. I feel so awful on mirt i just want it gone.
I have been on Mirt since end of May… different doses. I was also on 45 at one point, then 30. Mirt helped me a lot 6 years ago but not this time… and it made me even worse. It helped with sleep and made me eat so much crap! Are you still on Ven? If you are on another antidepressant whilst tapering Mirt, you should be fine.
Hi Karen, how is sleep now? Have you tried your antihistamine tablets yet?
I am still on ven. Maybe i can go faster.
Have a toddler so being very cautious
How is your depression? What dose of VEN are you on? I have been on VEN for 11 weeks but still not myself. It’s my 6th week on 225.