Synonyms: infantile polycystic kidneys, polycystic kidney and hepatic disease type I
Autosomal recessive polycystic kidney disease (ARPKD) is one of the most common ciliopathies with kidney (nephromegaly, hypertension, renal dysfunction) and liver involvement (congenital hepatic fibrosis, dilated bile ducts). Pulmonary hypoplasia may also occur. Clinical features also include growth failure and neurocognitive impairment.1
This is a companion discussion topic for the original article at https://patient.info/doctor/paediatrics/autosomal-recessive-polycystic-kidney-disease