Have you had your blood pressure checked since you started on the leflunomide, a rare complication of taking Leflunomide, that I had, you feel terrible if your blood pressure is too high, let alone being dangerous.
I can manage 10mg of leflunomide, with very little side effects, and no blood pressure issues, Dr suggested I take in the morning, but cannot tolerate the diahorea if I take in the morning, so I take at night, and then in the morning when I get up wooosh, and i'm in the clear for the rest of the day, family know to keep that toilet clear because there is no waiting when you need to go you need to go.
MTX, you can take as an injection, I do, and I was a little needle phobic, still am, but local GP helped me through the first few times I had to inject, a nurse could do the same, seems I also have the issue of not taking up MTX through my stomach, so getting very little value for swallowing them.
Salfasalzine and I do not agree with each other at all, itch like mad thing, it seems I have a sulfur allergy, and even though Leflunomide are sulfur based, maybe thats why I have high blood pressure with them, I can tolerate the lessor dose just.
Dr recently put me on Palquenel, sorry spelling, it seems to have settled down my arthritis, but at the same time I have cut out ALL MY WHEAT, NONE, NADA, within about 6 hours I could feel the difference, something happened, but the swelling in my joints that was really getting bad seems to have settled, fingers crossed that it stays that way, and I will keep away from wheat for while longer, due another blood test soon to see what my ESR AND CRP or are how high, I just know that it will be less than usual I hope.