Calprotectin level 1800 but colonoscopy was fine?!

I’m 50yrs old and recently saw my GP  because of ongoing bowel issues - constipation, mucus in bowel movements etc. He got me to do a stool sample and my Calprotectin level came back very high at over 1800! Normal is under 50.  Dr then sent me for a colonoscopy that showed nothing wrong except Diverticulosis.   I know a reading that high is usually indicative of IBD but colonoscopy didn’t show anything sinister. I feel fine at the mo.  I’m just so confused why the stool sample showed that very high level.  What could have caused that to happen?  GP is now away for 2 weeks.  So i’m unable to discuss it with him. Has anyone else had such a high reading and everything has been ok?  I know it’s not normal.

Hi Alison I had a calprotectin of over 6000.  I too had a colonoscopy which showed inflammation but no evidence of crohns disease.  It could be an infection which is what they think I had.  I would probably have it retested but make sure you have symptoms when you do to get an accurate result.  I think with crohns its not just the calprotectin test they go by but also your symptoms.  Many people think calprotectin Alone is suggestive of crohns but there's many reasons for a high result.  Many doctors go by the symptoms and not the result.  

Also the most common symptom of crohns is diarrhea not constipation.  

Thank you Jane.  This is really helpful xx

I would have to agree jane60128.