hello everyone. i have been suffering severe depression and anxiety for nearly a year. tried citalopram first but only lasted a day as it caused severe upset tummy (i have no colon). Then into mirtazapine which helped me sleep and no real side effects other than some migraines. no improvement either so doc switched me to duloxetine and told me to take first dose day after last dose of mirt. that night i developed seratonin syndome and spent 4 days in hospital. taken off meds to 'wash out' and sent home with diazepam and promethezine for the anxiety. 3 weeks later back in A&E with uncontrollable suicidal thoughts and refferred to psych home team. they put me on quetiapine and agomelatine, which did nothing. i could not reach therapeutic dose of quetiapine as made me feel too spun out. . psychiatrist went off with stress and a new doc stopped the agomelatine and added the mirt back in 15mg, insisting i increase to 30 and also increase quetiapine. again could not tolerate either increase as felt much more anxious and hyper but with severe brain fog. yet another doc has stopped the quetiapine but again insisted increase of mirtazapine but two days at 22.5mg sent me reeling. stuck back with 15mg for a couple of weeks then had to start back to work as sick pay ran out (from home on phased return) and just cannot think or concentrate, my brain is like treacle and i am still severely anxious. tried 7.5mg for two days but could not sleep and added promethazine and oh my god worse than before! so went back to 15mg for a bit but i just cannot function on this drug, i am like a zombie on speed, it seems to make my brain hyperactive but cannot order my thoughts so i end up sitting and ruminating or looping on research or starting one task but not being able to finish it. i can take half an hour to choose a t-shirt or go outside 10 times to check the weather before leaving the house. i am too scared even to go to the shops because it is so overwhelming to think or make decisions. i feel drunk or stoned all day until about 5pm but sleep is not good. i try to sleep a bit in the day with valium just to escape these feelings but that does not work either as my thoughts are still racing. last night i did not take the mirt at all as i felt desperate to get some clarity back but had to take promethazine to sleep and still 'off my face' today. i know i need help for my condition but mirt seems to be really stimulating for me, not calming at all, and the brain fog and disorientation is unbearable. i feel like i am under water. i have been on it for 6 weeks this time but cannot cope with giving it longer. i have a call with the psych doc tomorrow and presume she will tell me to go back on it or try a different ad but i seem to be so sensitive to side effects and it will be another long road of getting the mirt out of my system and starting something else, which probably won't work either. i have to be able to work but on mirt i am just staring at my screen terrified of not being able to focus at all. trying yoga and meditaion and breathing exercises but not helping. does anyone else have this experience of feeling really hyper and more anxious but 'brain disabled' at the same time on this drug? i am at the end of my tether. also gives me gut issues, vertigo and my hair is falling out :-(
mirt did not work for me either! did not take away depression at all and in all honesty I think some side effects which are like headaches when i think of something “harder” I experienced only after I was on it! Also all i was doing was sleep all day and felt stoned!And th headaches after thinking harder i never had before so I think its not a good drug at all! I am now on venlafaxine along with valium. for 10 years i was doing so well then i started having issues with all ADs so im still trying which might eventually work! wish u the best!