Charcot-Marie-Tooth (CMT) disease is a heterogeneous group of inherited peripheral neuropathies in which the neuropathy is the sole or primary component of the disorder.1 The typical CMT phenotype involves distal limb muscle wasting and sensory loss, with proximal progression over time. However, disease course is varied, reflecting both genotypic and phenotypic heterogeneity.2
This is a companion discussion topic for the original article at https://patient.info/doctor/charcot-marie-tooth-disease