Citalopram to Sertraline

Hi folks, been on citalopram for 8 years now, apart from a brief time on miratzipine 3 month last October to start of January, then back on Cit since, however the mood has never really lifted 5 out of 10 at best and the last 2 weeks more like 3 out of 10. So been back at the docs and switching to sertraline 50mg then a 100mg after 2 weeks, has anyone done this swap, and were there side effects, when I swapped from cit to miratzipine last year there was little anxiety but nothing major, the miratzipine made me angry so had to come off it.

Sertraline good drug, but you need to increase the dose To 200 grams daily basis and the best times to take the dose is 19:00 p.m the same time every day Do not smoke or drink alcohol and go to sleep early and wake up early. And drink a lot of water, and do deep breathing exercise (25 times) Or more every day especially in the morning and in the evening before going to sleep.

And continued on with breathing exercise until you feel better. 

all the best.

jimm

Thanks Jimmy, I was on 20mg cit, do you think I would need 200mg sertraline

Hi Nick, I wouldn't be surprised if it was actually coming off sertraline that caused you to feel angry rather than mirtaxapine as I felt angry and aggressive coming of sertraline.  I guess you tapered off over two weeks or something like that, which is pretty short, but in any case I would imagine angriness is a withdrawal symptom you have to put up with until your brain biochemicals rebalance.

The dosage of sertraline is completely dependent on the individual and severity of illness.  This should be decided between yourself and your doctor after discussing how you feel as you progress from the lowest therapeutic dose to a dose that works.  There is no perfect dose or time to take sertraline - you have to work this out for yourself based on how you react to it.  Some people find mornings better, others before going to bed, it just depends on how it works best for you.  SSRIs reach a steady state in the bloodstream after a few days to a couple of weeks, depending on the drug, but side effects may be reduced by taking the drug at a particular time of day.  Work with your GP to fine tune the dosage and other concerns as s/he will have experience of these things.