Cambio de Citalopram a Sertralina

Hi folks, been on citalopram for 8 years now, apart from a brief time on miratzipine 3 month last October to start of January, then back on Cit since, however the mood has never really lifted 5 out of 10 at best and the last 2 weeks more like 3 out of 10. So been back at the docs and switching to sertraline 50mg then a 100mg after 2 weeks, has anyone done this swap, and were there side effects, when I swapped from cit to miratzipine last year there was little anxiety but nothing major, the miratzipine made me angry so had to come off it.

Sertralina es un buen medicamento, pero es necesario aumentar la dosis a 200 gramos diarios y la mejor hora para tomar la dosis es a las 19:00 horas, siempre a la misma hora todos los días. No fumes ni bebas alcohol, y duerme temprano y levántate temprano. Bebe mucha agua y realiza ejercicios de respiración profunda (25 veces o más) todos los días, especialmente por la mañana y por la noche antes de dormir. Continúa con los ejercicios de respiración hasta que te sientas mejor.
Todo lo mejor.
Jimm

Thanks Jimmy, I was on 20mg cit, do you think I would need 200mg sertraline

Hi Nick, I wouldn't be surprised if it was actually coming off sertraline that caused you to feel angry rather than mirtaxapine as I felt angry and aggressive coming of sertraline.  I guess you tapered off over two weeks or something like that, which is pretty short, but in any case I would imagine angriness is a withdrawal symptom you have to put up with until your brain biochemicals rebalance.

The dosage of sertraline is completely dependent on the individual and severity of illness.  This should be decided between yourself and your doctor after discussing how you feel as you progress from the lowest therapeutic dose to a dose that works.  There is no perfect dose or time to take sertraline - you have to work this out for yourself based on how you react to it.  Some people find mornings better, others before going to bed, it just depends on how it works best for you.  SSRIs reach a steady state in the bloodstream after a few days to a couple of weeks, depending on the drug, but side effects may be reduced by taking the drug at a particular time of day.  Work with your GP to fine tune the dosage and other concerns as s/he will have experience of these things.