Another quick tip: I eat half of a small bag of salted potato chips a couple of hours before bed and this has really helped a lot with my nocturia. The salt helps the kidneys retain water during the night so it doesn’t get dumped into the bladder. Of course monitor your BP but mine hasn’t changed over the past year and is ok.
Thanks. I will try that as well. Half a bag is perhaps the calories in a cookie…or three.
I googled what you suggested and got back the following: “Its oral bioavailability is 64%, and its absorption is not affected by food. Therefore, alfuzosin can be taken without regard to meals.”
I’ve fooled around with the diuretic, Lasix. Taking it at bedtime should make your nocturia worse. I’ve tried taking it at 5pm (20mg or 40mg) to dehydrate me a bit before sleep, and it works somewhat.
There does seem to be conflicting information. If you check out this google result:
UROXATRAL® (alfuzosin HCl extended-release tablets) - FDA
you will see on page 2 an hourly chart of alfuzosin under fed and unfed conditions.
"As illustrated in Figure 1, the extent of absorption is 50% lower under fasting conditions. "
The language I saw when googled notes that absorption is diminished by 40% if taken on a “fast”. Not sure if they mean “fast” literally or not. To be sure, I
I’ll b e happy to take at the morning meal as their seem no other side effects for daytime use (driving, etc.)
Owen: If you check out the chart on page 2 of this google result:
UROXATRAL® (alfuzosin HCl extended-release tablets) - FDA
you’ll see a graph that shows that that under fed conditions, the concentration of alfuzosin reaches a maximum about 8 to 10 hours after it is taken. Since most potential issues for men occur at night, I take my alfuzosin with my evening meal, so that the maximum concentration of alfuzosin is available in my blood around 2 to 4 am in the morning. Just a thought.