There is a range of congenital nose problems - some occurring alone and others as part of a syndrome, most commonly the craniofacial syndromes (eg, Apert, Fraser and Binder syndromes are all associated with a degree of hypoplasia). The underlying causes are varied but, as with any congenital disorder, they can be broadly divided into chromosomal abnormalities (mutations and inherited problems), diseases associated with prenatal infection, maternal drug abuse, environmental factors, iatrogenic causes and abnormalities of unknown aetiology. These are generally uncommon conditions, occurring in <5 in 10,000 births.
This is a companion discussion topic for the original article at https://patient.info/doctor/congenital-disorders/congenital-nasal-problems