Cymbalta and smoking

Does anyone notice that smoking affects you while taking Cymbalta?

I don't smoke but my worst was drinking coffee when my liver enzyme was high ALT.  They coffee is good for liver.  I'm back to drinking coffee. It was like had I had to force myself to drink coffee but yet it made me feel worst.  I'm ok with coffee now. I lost my trust in doctors and I really don't like the path I'm on right now.  It feels like I'm slow motion and basically feel like my next step is to wait for my death which seems nearby.  I need to find a solution. No help from medical field. It's like I'm on my own.  It's like people took all my money and deserted me.