Extreme fatigue....AD'S or Betablockers?

I have been on and off anti depressants for several years but 6 months or so ago i felt they werent working. my gp changed me onto 40mg fluoxetine plus 2.5mg bisoprolol.

For the last 4 or 5 months I have been dealing with extreme tiredness, exhaustion in fact, I’m struggling to get up and feel horrendous.

any experience of these 2 meds and any advice?