I was on sertraline for 5 months but it didn't really work for me, I got a evaluation of a pyschartrist and she recommend I should be on venlafaxine. A week ago I did the switch over from sertraline to venlafaxine and have been okish until yesterday my anxiety is through the roof! I have depersonalisation disorder anyway but I am feeling more detatched and I feel like im not really here, I'm stuck in my head which makes me more anxious. My brain hurts and eyeballs hurt, I've lost my appetite, feeling unreal (not like in a cool teenage way lol!) and feel like im not me! I'm so fed up of feeling like this everyday I've not felt properly like myself for 13 years when my anxiety started but the past 6 months my anxiety has been severe! Anybody else felt like this and got better, I'm praying for venlafaxine to work. Also I have a appointment with one of the UKs top pyschartrist in 2 weeks which I'm looking forward too (its to do with a law suit ).