Where shall I begin… I started taking 50mg of Zoloft and increased to 100mg for depression which has caused me to gain 30 pounds in a matter of months!!! Needless to say this weight gain has me more depressed than ever because it will not come off!! I have recently been taken off of it from my doctor by weening me off of it. I have never weighed so much in my entire life .. not even when I was pregnant …: I have tried EVERYTHING to help me lose this weight from going hard in spin class 4 days a week or so and going on the Keto diet… NOTHING has helped me and I have only been off this medicine for a week or 2… has anyone else experienced this nightmare from Zoloft?