About the side effects. How are you all coping with yours?
Be extremrly careful and conscious on this chemo medication. I refuse to take this due to my experience and the majority of others experiences. Really do your research. It is an option that caused me so much toxicity contributing multiple other conditions and infections.including dental which systemically caused much pain.
Hi Karen470.
I am a new member here. i am a 53 year old male. active, dont drink or smoke.I started takeing methotrexate 2.5 mg x6 once a week and 1 mg folic acid every day. on august 15th 2015. this is to treat psoriatic arthritis, psoriasis on skin and fingernails. i have found the worst side effect is the negetivity, fear and ignorant based posts we find on most internet sites! watch out for the negetivity. the worst physical side effects for me was some temporary small sores inside my lip now rare to non existant. a couple of headaches and rare nausea. i had headaches any way i have kids. and the medication is working. just had liver (blood) test and they look great. this medication has been around a long time. read about its history and listen to your rheumatologists encouragment.above all be patient.
Hi Karen. Bless you. It does seem a frightening journey. All I will say is some lucky people get away with very little side effects. Some get more and some don't tolerate it at all. You need to find your own journey with it. Hopefully you will be as lucky as Mr Todd. I have been on it for around about a year now and suffered terribly the first time round mainly due to infections due to lower immune system. Second time around I am tolerating it far better and the difference in my pain level is amazing 😊 Make sure you get your bloods tested regularly and see how you go. Take any infection seriously and go to the doctors if you feel you are unwell so it can be treated quickly and mouth ulcers etc use this site for advice. I learnt nearly all my tips from this site that actually work because people have been through it. Keep positive! Try it. Don't be scared of it but be more aware of any changes in your body like fever, ulcers etc. I wish you luck on your journey. Lisa sending ☀️☀️Thoughts 😊😊😊
Bless you. I hope you have found something which works for you now 😊☀️
I've deleted the argumentative posts here. Posts are users own opinions whether positive or negative. In forums like this the majority of posts will be negative but please do not get into debates or disagreements as this just discourages users from posting.
Regards,
Alan
Thank you. I agree I didn't word mine very well but tried to apologise but I think the whole conversation being deleted was best 😊
Hi Mr Todd
First dose and no side effects, but have noticed the psoriasis clearing from my arms YAY lol sorry if my post caused trouble have not been on here for a few days as I have the dreaded seasonal bug that is doing the rounds lol thanks for your informative post and glad it worked for you
Hi Lisa
Thank you for your reply, I have my first bloods tomorrow, hopefully nothing bad will show 
lol sorry my post caused you some grief <3
Dear Karen 470,
I am Glad to hear this medication is working for you.
The witnessing of the psoriasis clearing away from my skin (not completely gone, but mostly) is something i am most greatfull for. it was emotionally disturbing to me.
yesterday, i looked at some some pictures of my psoriasis areas that i took when i first started takeing the methotrexate. the difference is impressive. Get well! I hope and pray it works out for you.
No grief my lovely. There will always be a difference of opinion as we all this tolerate it differently. When you get into the swing of it you will be able to work out which posts relate to you more 😀☀️☀️ Lisa
Thank you Anna. I wish I had never taken the first dose 
The markers on my liver are now raised more than normal and the last two days I have rather large swellings on the back of both of my legs above the knee, no pain in them so I am putting them down to this drug. I am going to the doctors on Monday to get them checked out hope you found something for you xxx
Hi Mr Todd, after 13 years of suffering with psoriasis I was finally given UV treatment by the hospital, immediately following my treatment my skin flared up again and i'm now told Methotrexate is really my only remaining option. I was told to reasearch the drug prior to making my decision and to be honest all I have found is negative/off putting comments on forums. I have registered to this forum following your post and would really appreciate it if you could take the time to tell me more of your experience with the drug. Kind regards