High LDH, Serum value of 277 U/L

Digestive health
1

I recently took a full body test and they show a high LDH, Serum of 277. What should I do?

I showed the reports to a physician and he gave me medicine of cholesterol and high BP (the test shows 205 LDL cholesterol). When I came home, I found out that he ignored the high LDH in LFT test.

2

Hi,elevated LDH levels are a nonspecific factor,so i cant really say much without looking at other tests.When you say LDH was tested,do you mean iso-enzymes LDH4 and LDH5,which are found in the liver or LDH in general?What are the levels of AST,ALT,ALP,bilirubin,albumin?

Also LDH can be elevated due to alcohol usage and thrombocytosis.

3

I've uploaded those values:

Moderator comment:I have deleted the links to the images as they went to a site unsuitable for inclusion in the forums. Users can upload images directly to this site by using the icon at the top right of reply boxes.

4

Hi,can you write them down since the link was deleted by a moderator.

5

Yeah, sure. I've also included the reference intervals.

Liver Profile- (Liver Function Test)

Protein Total@

Serum

Biuret method

7.9 g/dL 6.0 - 8.3

Albumin@

Serum

Bromcresol Green

4.6 g/dL 3.5 - 5.0

Globulin*

Serum

Calculated

3.3 g/dL 2.3 - 3.5

A:G (Albumin:Globulin) Ratio*

Serum

1.39 1.20 - 2.00

SGOT/AST (Aspartate Amino-transferase) @

Serum

NADH (without Pyridoxal-5’-phosphate)

18 U/L 5 - 42

SGPT/ALT (Alanine Amino-transferase) @

Serum

NADH (without P-5’-P)

38 U/L 6 - 55

GGTP (Gamma Glutamyl-Transferase) @

Serum

L-Gamma-glutamyl-3-carboxy-4-nitroanilide Substrat

32 U/L 12 - 64

Bilirubin,Total@

Serum

Diazonium Salt

0.78 mg/dL 0.20 - 1.20

Bilirubin, Direct@

Serum

Diazo Reaction

0.31 mg/dL 0.00 - 0.50

Bilirubin, Indirect@

Serum

Calculated

0.47 mg/dL 0.10 - 1.00

LDH, Serum*

Serum

IFCC- Lactate to Pyruvate

277.00 U/L 125.00 - 220.00

6

Moderator,

There was no option to upload pictures directly to this site.

7

Since everything in the LFT is normal we can exclude liver disease.As i said LDH is nonspecific factor so it will rise even when there is something minor, like inflamation.Elevated LDH that is up to 5 times over the normal range usually means inflamation,mononucleosis,pancreatitis or parenchymal liver disease(in your case we can exclude this).If the results were like 5 to 10 times higher then the range then it could be something serious.If you have no other symptoms you are just fine.Also do you have CBC and differential done?

8

I had also got my CBC done. It's all normal. Lipid profile as well; only cholesterol is high.

My doctor said no need to worry about the high LHD, he has given me the medicine.

But I came home and found he prescribed me for cholesterol and high BP only. Maybe he meant LHD will become normal on its own.

9

For sure he had the LDH in mind.In a week or 2 it will go down

10

Thanks.