Synonyms: congenital aganglionosis, congenital megacolon, megacolon congenitum
The underlying pathology is an absence of parasympathetic ganglion cells in the myenteric and submucosal plexus of the rectum, possibly extending to the colon.
This is a companion discussion topic for the original article at https://patient.info/doctor/hirschsprungs-disease-pro