i'm on the week 3 of methotrexate and now they have double d my dose two15mm

does anybody know how much does it keep going up in another couple of weeks they are adding something else to it to make it work even better they said . bit worried my eyes are not right and i'm getting pains in my chest more than normal any help in words would be good thanks max

The maximum dosage is 25mg. But if you are feeling anything not right you shd talk to your doctor..

I take 8 tabs per week so 20 mg which I think is the highest dose.  I thought that was what my Reumy told me.  I would also be interested to hear if there is a higher dose than that.

Really? My reumy told me 10 tablets is the highest which is 25mg. I'm taking 5 tablets now but I'm sure my reumy will increase my dosage on my next appointment which she already wanted to do from my last appointment. Are you feeling any side effects?

Hi Max, I was started on Methotrexate in early May. I was told it would take 3 to 4 months to become effective. It did take that long. I take 8 tablets every Thursday. Each tablet is 2.5 mg. I also take 2 tablets of Plaquenil per day, 5 mg Prednisone & 1 tablet of folic acid per day. I feel pretty good most of the time except for fatigue. I HATE taking these medications but was in horrible pain until I was hospitalized & diagnosed. I can function now.

I hope everything works out for you. Good luck.

Yes, my side effects are a lot of fatigue and sometimes upset stomach.  Right before he upped my dose to 8 he had my try injections.  That made me really nauseous so I went back to the tabs.  The day after I take the tabs I just don't feel good all the way around.  I often get back pain but have found out that if I drink lots of water especially on the day of and day after taking the Mtx I don't get the back pain.

Max you need to tell your Doc about any chest pains you may be having. I have not heard anyone else having chest pains on MTX.

I was started on 10mg of Methotrexate which then built up to 20mg and two folate tabs the day after. It took a while to kick in so they added Hydroxicloroquine too.

I thought that 20mg was the highest dose of Methotrexate they would give, maybe check they have you on the correct dosage, there are so many news items at the moment saying how dangerous it is to be given the wrong dose.

  My doc told me she has patients that take 25 mg MTX.    I could not tolerate it

You need to call the doc and let them know about the chest pain and about your eyes

    I did feel like I had mild chest pain and that was only taking 10mg dose 

Hi Max,

I am taking 25mg, which is 10 tablets. I did some research and this appears to be the maximum dose. I am also on HyIt hasn't helped me and I'm now on a biological injection which has helped.

I would definitely speak to someone about your chest pains. I had to have a chest c ray before they put me on

Hi max i am also on 25mg of mtx and i still get flare ups every 5 to 7 days i just took mines yesterday all 10 tablets thats the highest dose yes it can really knock ur body up the side effects theres not a better drug out there for RA a nurse told me its the gold star treatment for RA tho u have booklets to read about mtx and u get told wot side effects can happen we are all in the same boat here and just have to battle on best way we can...good luck mate..

Thanks bob i was moved into a sheltered home not so long ago only 58 years old went from  bad to even worse after son died so upsetting they say that's what might have kick started ra thats what they said nobody knows for sure  i felt i was on my own for some time i am but i think i have a battle left in me still one more for sure if i told you proply what a bad year i had be to upsetting lost everything in the world my home dogs wife just ayear from hell all the best mate max 

You are not alone . You have all of us here .

Hi max hope ur feeling ok today mate am 51 myself living with RA i live in scotland cant even begin to imagine wot u went through and still are after losing ur boy really sorry to hear this max losing my sister few yrs back was bad enough for me but one of ur kids totally devastating max...yeah i would agree when you said losing ur son could have started the RA in ur body it could take something like that i do believe it keep that battle spirt in u max try not to let RA get u down tho i know it can be very hard at times my god u have had at very hard time of it really feel for u mate try keep up ur fighting spirit max ur boy would be well proud of u pal hang in there max feel free to message me at anytime for chat try be positive tho after all u have been through i dare to imagine i love van morrison max and when i have bad flare ups van and his music get me through the painfull RA moments max ur a gem of a guy u be strong my friend u hear....all the best buddy🎶🎶🎶👍👍👍👍👍👍👍👍🍵

Thanks bob very kind words all the best to you and your family max

Hello everybody max here my feet are burning my ankles are swollen my hands and fingers hurt joints ln arms are killing and shoulders is this normal with RA my thinking side of things is not right and i'm triping over my own feet alot which are making me have a lot of accidents around my bungalow not managing on my own very well it this normal 2  all the best to everybody max

Max did you call the doc about your chest pain?   you need to speak to someone.  I think they need to start that 2nd medication already and /or prednisone.   But I will let other chimes in that have more experience than I do.   Hang in there,  they will find the right meds for you.  We are all routing for you

Hi Max, unfortunately burning feet, ankle pain, finger pain etc. are all symptoms of RA. It takes a while for MTX to kick in and so they usually prescribe Predislonone for a while too. They also prescribed Hydroxycloroquine for me too. Although they helped I still had massive inflammation (hence the burning sensation) in my hands and feet so after a bone scan to see where the inflammation was they put me on a biologic fort nightly injection. It's a guessing game as to which meds help each person the best which is why they will try different things. I am now just on half (10mg) dose of MTX as liver damage occurred on 20 mg, and a Cimzia injection every fortnight but can also take Predisnolone when and if needed, I also keep Endep in to help me sleep and Palexia pain relief if things get bad.

make sure you get a good rheumatologist, one that you can call if things are bad and who will make time to see you, tell them how bad things are for you and don't be afraid to ask questions. We are here too if you need friends who are going through the same thing. Good luck.

THanks mary its nice to talk to people in the same boat it makes you feel your not on your own all the best to you max

HI max, sorry youre having probs with mtx. I had dreadful problems and tried really hard to tolerate increasing dose as I was also told only 25mg would work! I felt truly dreadful and had zero quality of life. I dont take it at all now, had to manage with 6 weekly cortisone injections for quite a while and now have a biologic. Also I had pneumonia and the consultant related it to methotrexate use. I guess it just didnt suit me, though many folk do ok on it. You may be one of those it just doesnt suit. Tell the doctors,, dont hesitate to say how bad youre feeling, there are no medals for suffering in silence . Good luck, I feel sure you will find the right medication, there IS a light at the end of the tunnel!

Big thanks to you treezsh i worried at the moment i got up in the 0330am and took more of the methottrexate it should  have been prednisolone because i forgot to tale it earler i should not have taken the methorexate until friday coming my mind not right some where will see doctors again next tuesday they take blood every fornight and that's when i see the doc but a big thanks sometime you do feel on your own and its nice to here possive words thanks again .