Lanzaprozole for LPR Side effects

Digestive health
1

Hi I have been diagnosed with LPR after seeing an ENT specialist 6 weeks ago. I am now taking 2 x 30mg Lanazaprozole (PPI) a day (morning and before evening meal) and also 2 x 5ml (teaspoons) of Gaviscon advance 4 times a day after food and before bed.   Since taking this medication i am getting constant wind in my stomach accompanied with bubbling, growling noises in the stomach straight after eating. and also a very bloated stomach especially after the main meal in the evening. Has anyone else experienced these side effects??

Thanks Pete

2

Sounds par for the course Pete. But we are all different, I took those ppis and eventually got terrible side effects, unbearable, others are fine with them. I switched to bicarbonate of soda and sometimes lemon juice as if you only take a little you dont get side effects. But I have read posts where people say they took a lot more bicarbonate of soda than I doand they are fine where that would give me bad side effects.

3

Many people have the same problems and it is one of side effects they mention yeverywhere. 

4

I use to take Prilosec and got lots of noises in my stomach. The longer I took it the more bad effects it had on me to the point I quit taking it, I feel a lot better not taking anything at all. What do you mean "Wind in my Stomach"

5

Hi Peter 67- this is a horrid condition as your finding out unfortunatkey,and what I have quickly realised it effects different people in various different ways - 

i have tried various PPI they all have horrible nasty side effects, which make you feel worse in others ways headaches, stiffness and generL feeling of unwellness.

i have been prescribed Ranatadine and have taken for about 5 years 1 @ night or if I need a top up 1 in the day - I normally take just the one at night and if needs be top up with Gaviscone extra.

a few months ago my reflux was really bad , starting with a sore tongue, bad taste in my mouth along with throat clearing, spitting up the mucas and a very hoarse throat and really on able to tolerate drinking water, anything I ate made me feel full and a lump in my throat - horrible -

After exstensive research myself and good information on this site from other sufferes I have calmed the whole reflux thing Down

I down loaded a list of alkaline foods and tried eating and using mainly alkaline foods, introducing them to my diet, eating broccoli , leaf spinache even putting on my salads or putting in my sandwich instead of lettuce, eating tomatoes, sometimes grilled on un buttered toast, ( check out the list it's pretty exstensive including fruit

( you will be surprised the foods which are high in acid and agrivated reflux - oats porridge for instance or muesli, sultanas bananas - it's worth checking out.

only drink decaf products as others create acids - drinking water ( Tesco ) most branches - a water with a high PH level of 7.  7 or higher it dilutes the acid as does drinking a glass of water with lemon juice - crazy it sounds but it's. Different type of acid from stomach acid and helps dilute the stomach acidity.

i eat a handful of almonds daily this also dilutes the acid chewing them thoroughly helps neutralise the acid.

try looking at the site water for life on the net , a lot of helpful info there , finally stress and anxiety aggravate reflux or can cause a bad bout to come on

try grazing when eating , little and often not big meals, and try not to eat after 7pm to allow your food to digest before bed time , and finally  if you feeling full try sitting upright to help your food to go right down and not get stuck.

i hope I haven't noted you , I'm trying to help as when mine was bad it was just unbearable , I had this on and off for quite. While, mines quiet at the moment , but I think before I eat anything it's become a habit now, albeit I'm slowly introducing a glass of white wine occasionally now or a vodka with the magic water if out socially 

good luck - I think you will find most people have horrid effects from these meds, and if on them a long time coming off the reflux can become worse- a catch 22 situation 

you can only make an informed personal choice ... Best wishes to you 

6

I don't think that Lanazaprozole is to blame. I've not had that reaction to any of the PPI's.

That is a lot of Gaviscon and four meals a day seems a lot to be  eating. Hardly gives your food time to digest before the next meal.

7

I have been taking PPi's since 2001, some worked for me others didn't but I have not felt any side effects from them.

The only time I had a problem was when taking antibiotics with them as in triple therapy.

8

thanks for the lenghy reply. I didnt realise muesli was high acid . I have a bowel of Alpen Muesli each morning for breakfast. For luch its usually a sandwich of ham or other meat like pork or turkey and a packet of walkers baked cheese and onion crips. Then a main meal which varies from potoatoes, carrots, green beans , broccoli, whith lamb, chicken etc..or spagetti bolonise (one day only) noddles with chicken and souce (one day only), white fish with potatoes and vedge, I occasionally have a round of toast for breakfast and a snack most evenings like a yougurt or small cake... Nothing to excessive in my diet and i dont drink only squash or water. I have stopped drinking normal tea and now drink camomile tea only with a little sugar. My symtoms of LPR are not extreme but these side affects (constant noisy stomach, bloating are :-(

9

That's great. Derek - I'm glad that you can take them but be aware they can cause oetioprosis in both men and women in long term useage - just trying to help as I have done a lot of research on them - it just making a personal informed choice at the end of the day and I really don't tolerate them well 

10

Hi Pete - beware that red meats and pork create stomach acid where as chicken doesn't - orange squash is acid in the wrong way it creates more tummy acid whereas lemon juice in water dilutes it - bizarre I know.

Crisps blimey your chancing your arm their buddy and cheese and onion , that's a big bad guy for acid- the best way to enjoy your food and eat well is little and often - grazing as they call it - you need 3 hours for your food to digest - maybe with your large meals your tummy and digestion system can't cope  hence the Hubble bubble noises

read water for life on the net - that gives you a good insight to the right foods. Etc ------- cheers for now 

11

You are looking at things in very black and white terms. A person who has a big build has no risk of that, only a very skinny person with small bones. And you an offset such things by taking extra vitamins or minerals or both.

12

dfferent books and sites give different opinions. Most say that ALL meet is acidic butwhite meat less so. And there are lots of people who can eat all the "wrong" foods and it makes no difference.

13

Well - I have been advised by both my GPand the GI consultant I have been under for the last 8 years ( GI consultant is via the private sector) that I need to be aware they can cause osteoporosis  long term useage, as written in the enclosures - bone structure is irrelevant.

As I said in my response it is a matter or personal informed choice- good diet is important - you cannot rely on medication alone to keep you reflux free - some effort has to be applied by your self by avoiding products that can aggravate - but hey ho!! Everyone is entitled to their opinion and has to do their own personal research and interprete as they read it.

My opinion is based on good I research medical information from doctor I trust --- it works for me I shared my research and what has worked for me- it really is up to the individual to do it for themselves I suppose to find the right formula that suits their lifestyle -- 

14

Sorry Carmel - I think your responses are a bit blinkered, if you have the condition and rely on med to control it , then eat wrong foods - that surely is a recipe in the long term for agrivating the condition.

Using minerals and vitamins are no substitute for as a good healthy diet to suit your health needs - we obviously have different view points on the matter - which is  healthy for the conversation on the site.

I myself know what works for me,and know what I believe in which is done by research and speaking within my private medical sector - whom could make more financial gain by issuing more prescriptions BUT don't - better information on how to manage it ( so I feel lucky I have them to support my needs )

15

Lack of stomach acid can also allow polyps to grow. Some women complain tht PPI's affect their libido.

The Oetioprosis effect can be avoided by making sure that you increase or get enough of certain vitamins.  

Tagamet was the drug that  had the worst reaction for me as it affected my kidneys when taking it.

16

I dont rely on medication. I use none whatsoever for it. ACV is a way to make the body more alkaline, no diferent to you drinking yojr bottled water. I also drink lemon juice for same reason. Bicarbonate of soda is same thing.It is blinkered to say that eating vegetables tgive you all of the vitamins and minerals you need when an average cabbage now contains about 5% of the vitamins it woul dhve contained years ago. You could not possibly eat enogh vegetables if you sat eating them all dsay long to get the minerals and vitamins you need. Before I changed my habits my reflux was much worse and used to go up in my ers nose and head all of the time.

17

Cimitidine affected my kidneys and made me ill for a while. Of course the doctor says you are imaginging things and he has neer heard of this before.

18

Hi Wilkie,

there is a very good book written by world known American doctor specialized in reflux desease Jamie Koufman "Dropping acid the reflux diet cook book & cure" she has written this book together with a French cook and created safe recipes for people who suffer from this problem. 

So maybe you created your own diet that works for you but you are very wrong claiming that oat meal is acidic. It is one of the best and safe food for reflux. Tomatoes is one of the very worst along with any coffee even decaf. Though one cup of coffee is allowed a day. Bananas is good for most of people. Dr.koufman says also that the fact that lemon juice is good for reflux is a myth. It is indeed very bad. 

Besides that there is a reputable site of American food and drug administration about level of acidity of most of food where you can check. 

In Internet there are many crazy lunatics who without good knowledge claim that they know a lot something like lemon juice or apple cider is good for reflux. 

But you are correct that without dieting nothing will help. 

 

19

I have been prescribed Lansoprazole for 4 years and get various side effects which doc says is normal adding it's all about balance to control your gastric problems. I get bloated wind and sometimes visit toilet more than usual. Am trying to vary diet hoping for improvement but am worried about bone thinning in long term use of the drug.