Synonyms: LNS, hypoxanthine-guanine phosphoribosyl transferase (HPRT) deficiency
Lesch-Nyhan syndrome (LNS) is a rare hereditary disorder caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyl transferase (HPRT).1
This is a companion discussion topic for the original article at https://patient.info/doctor/neurology/lesch-nyhan-syndrome