Diagnosed hypothyroid >10 years. I have struggled all of this time to feel 'normal'. Drs have continually increased Levothyroxine to attempt to normalise TSH. Six months ago they prescribed 300mcg. The pharmacist queried this! I take it regularly, without food etc. I am still symptomatic and free T4 & T3 still low. Anyone else on this dose without effect?
300 is a large dose. You may need a different type of treatment if you are not responding and still have symptoms. I know how difficult it can be to treat for some people and everyone is different. What is your TSH now. I believe that some in the medical profession say you need to look at the complete thyroid function results but most gps just go with the TSH and also use an out of date range. There are those on this forum who know a lot more about this subject.
Also how are your vit D levels my own tsh changed after being on Vit D3. I think they say that hypothyroid patients are often low on this vitamin. Hope someone here can help you. I would think you need to see a specialist if you haven't already. Good luck.
Hey Im sorry to hear that... look up thyroid hormone resistance.... it is related to normal low t3t4.... but low or high tsh seen that you an have this from my opinion.... check on copper toxicity do you have a Cooper iud.. do u drink tab water.... if high on Cooper check if you have Cooper toxicity... after you reasses that if you don't have a Cooper iud or drink tab water and low cooper.... try taking a thyriod supplement... make sure it has thyriod L-trysione and other herbal supplement even a slight dose of cooper since Cooper is a hormone balance supplement ...our body is ran by gene therapy... by giving your body vitamins and supplements it restarts certain genes and makes them start working and start your body to regenerate organs and body in general....
Look up thyroid hormone resistance can be high or low tsh and sub normal t3t4.... and still can be hypo , or hyper...
It could be that rT3 is raised and if they go on increasing T4 Levo its bound to increase even more. From what I have learnt if this is the case you need to take T3 to lower the rT3. There could also be antibodies present. Another thing Doctors are not doing is to correct the adrenals. The problem in the UK is that the CCG's and Doctors are listening to the RCP not their patients. Another thing is that T4 is very cheap compared to T3 or NDT and the most likely reason for not prescribing it even on a named patient basis.
if you want be cured It called adipose stem cells and bone marrow stem cells... I have found three published areticles they are government legit... ncbi....cinical studies... over here stem cell procedure cost 5000-8000$ usd....but I know from research it works...it either fixes hormone issues and slowly makes thyroid issues disapear...not lying send me a private message will give u info.... I'm currently have to rule out my that my hyper/ hypo tsh and hypograndism is not caused by a pituitary tumor in the brain and will take stem cell..I will pull 10,000$ to just have my life back...please do your research to see what suits you
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Please post latest blood work tsh t3t4, state if gotten ultrasound od thyroid like nodules goiter thyriod cancer.... it will expand my mind and I can dig a deeper answer to help you out...
This procedure has not yet reached the UK let alone under NHS. Remember too a lot of thyroid patients are not well enough to work so cannot afford this expensive treatment.
Yes , vailed points. RT3, and VIt D.
Also read about Fibromyalgia in thyroiduk org uk
Apparently these two condition share same symptoms , so could be same underlying cause . So T3 might help both .
Doctors less than 40 yrs , ie, doctor graduated after 1990 would know about this condition better as it was only officially recognised and was given a name by American rheumatology society only recently.
but you mentioned your T4 T3 is low. ,
Read about the thyroid test , thyroid harmone transport in nahypothyrodism org , it will help you to understand how to read your results in reality.
Good. Luck ... Keep seeking answers if you don't feel right. It's not all in our head dear .
I totally understand it is important to do gene therapy with thyroid supplments and minerals to unlock the bodys chemistry to see if supplements and minerals can start the healing process.... I been reading that certain supplments trigger certain genes in the body and you just have to try til you find the supplements.... Gene therapy with chemo , herbal , and supplment are being studies on how it work on dna... which comes down to gen therapy...
I know in europe adipose and bone marroe stem cell is big over there over here I found three places in las vegas.. and two in California buy all are self pay clinical studies...fda cannot close these stem cells since these are not presidential stem cells nor embryonic. ...
The recommended dosage is 1.7mcg per kg of body weight. I only went up to this dose when I was pregnant. I can tell if my thyroid is underactive by my basal pulse rate, that is my pulse taken first thing in the morning before I get out of bed. If it's below 60 I'm undertaking, over 70 I'm overactive.
I have since found out my body is not doing the next bit of the process very well, that of converting T4 to T3. It is worth asking your doctor to test T3 as well as TSH and T4, to see if this is the case for you too. Ask for a copy of your blood test results and look to see the relative position of each result within its range. For example, if T4 is middle of its range, T3 should also be in the middle of its range.
Jeffcc, thank you for posting about the research into stem cells etc. I like knowing what is out there and may be coming in the future. These breakthroughs are often rare and expensive to start with, then become more more mainstream and cheaper with time. It gives me hope to know tthere is another treatment available, even if I can't afford it at its current price.
Hello Carolwebspresso:
I am a nurse and live in the USA. I have Hashimoto's thyroid disease.
It sounds like you have a problem like I had years ago. I took LEVO and never got my TSH normal. My TSH was never right despite raising the dose. I can't convert T4 into useable T3. Our thyroid is to take the LEVO which is T4 and make it into T3 by way of the thyroid gland. I was on NDT but now I am on just T3 called Liothyronine.
I suggest you try NDT which is a natural thyroid hormone made from the pig's thyroid gland. NDT contains all 4 hormones that your own thyroid would make. It is a much better replacement hormone.
Raising the LEVO is not the answer. Plus that dosage is not safe. See a good Endocrinologist who knows the thyroid better.
You also need a full mineral panel (blood work) to include, sodium, potassium, calcium, ferritin, magnesium, iron, and a vit. D level. Many of us have low vitamin D and there is linkage to thyroid disease. It is a special test and takes about 1 week to do.
Let us know how you do,
Shelly
I read somewhere that the average Armour Thyroid dose in England is 3 - 4 grains. This is the equivalent of 300 - 400 mcg's Levo. I thought this was very high. Does any one know if this is true or baloney?
Hello LAH:
1 grain = 60mg what I was taught in Nursing school so if it was 3 grains it would be 180mg.
XO, Shelly
Hello LAH:
I did the math 300mcg is equal to 0.3 mg.
1 grain is equal to 60mg. So at 3 grains 180mg 4 grains = 240mg. However NDT is formulated differently and that it is not a synthetic so that has to be taken into consideration.
XO Shelly
Shelly I have in front of me Nature-Throid one grain and it states t3 =9mcg and t4=38mcg Calcium 17mg and magnesium and sodium less than 1mg each.
I have also been seen by an endocrinologist today as my heart rate has been worsening in irregular bpm. She said that the T3 would be the cause in that NDT contains too much T3 to T4. She has therefore suggested I take 50mcg t4 and 10mcg t3 twice a day. She has on top of this admitted that something else is adding to my thyroid problems and I said YES the pain in my groin that is like glass sticking in and most likely caused by the mesh TVT. I have also had thyroid tests which also included FT4 and FT3 and have another test in one months time having been on the change of medication. Bear this in mind that other health problems can in turn affect the thyroid. There are also different arreas in ones body that convert the T4 to T3 the working hormone, but T4 is said to be longer lasting than T3. On top of all this the fact that I have been taking NDT suppresses the TSH and so does taking all T3 and according to the Endo it is suppressed due to too much T3.
Endocrinologists are non too pleased if the instructions on the bottle are not in English in the UK. Does this in turn apply to other countries who's patients are taking medications without their language on the bottle.
Shelly and Kathleen,
OK, I think I have the Rosetta Stone. I wrote back to that source and got a reply:
To Administrator
Please can you repost/repeat something I read somewhere but I cannot find it now? It was the average dose of Armour in grains. I thought you said it was between 3-4 grains in Britain. Was this correct? If I translate that to the equivalent dose of Levo I get 300 - 400 mcgs, which is very high. Maybe I am missing something, could you elaborate on this dose please?
Thankyou,
Lahs.
From Administrator
LAHs, I'm pretty sure it's Mary Shoman who says the average is 3-5 grains and that will be in the USA as NDT isn't widely used in the UK. It really doesn't matter what averages are, people need as little or as much as they need.
Manufacturers state that 1 grain is bioactively equivalent to 100mcg T4,not that it is equivalent to 100mcg. The actual T4+T3 content in one grain is equivalent to 65mcg T4 if you use a 3:1 T3:T4 ratio, or 75mcg if you use 4:1 ratio.
Admin.
I still have to give this a bit of thought, but there it is for the time being,
LAHs
Hello LAH:
Oh that is a good answer. I agree with that.
Shelly
Hello Kathleen:
I know other areas can help convert the T4 into T3 but since this is about low thyroid TSH or the like, I keep it simple. Of course the liver helps and intestines, other organs, etc,...but to answer in a person without giving a whole anatomy lesson and then some, I keep it simple to just the thyroid unless the person has no thyroid left.
I could really expand a lot but to the person reading it, I do not want to overwhelm them. Many people have no idea what a thyroid is let alone another organ, and the functions, etc...
In this conversation we are talking about her LEVO, and her many years of not getting good reults in "TSH LAND" and some of us no matter what the dosage or how it is absorbed, can't take T4.
I know other health problems like LUPUS, Cancer, Diabetes, etc..... can effect the thyroid so yes, if I want to write all of that I could...what is your question to me? I don't see a question.
I am writing to help people. I doing this from my knowledge of over 33 years as a nurse (RN). NDT contains all 4 thyroid hormones and has a 3:1 ratio per the administor of this forum. That means it is more T4 than T3. see answer to LAH below.
I am sorry your have a heart rate problem. Stay well, Shelly