Synonym: systemic mast cell disease
Mastocytosis is a mast cell disorder. Mast cells are found in the perivascular spaces of most tissues and contain pro-inflammatory and vasoactive mediators. These mediators are released after IgE receptor cross-linking induced by allergens or other stimuli.1
This is a companion discussion topic for the original article at https://patient.info/doctor/mastocytosis-and-mast-cell-disorders