My daughter suffers with them frequently due to a blood disorder that she unfortunately has and sometimes has as many as a dozen at a time.
She has tried just about everything possible to try and alleviate the discomfort they cause, without much success until recently. A mouthwash called Aloclair (now on the market) has really helped and coats the ulcer relieving the pain. It's not cheap though at £8.60 a bottle!
Have never heard of them been associated with ME, but nothing would surprise me to be quite honest ..... it seems to throw everything our way :roll:
Maybe at last there it is something that is not down to the ME. It is something I seem prone too. I have some paste called Adcortyl in orobase that works well. Only trouble is it sets, so I only use it at night cos it glues my tongue to my cheek.