In February of 2019, I had to go through treatment for colo rectal cancer (radiation and chemo). And the radiation really destroyed my insides. I had my second post treatment biannual check up yesterday and my Doctor said I have radiation proctitis . So he prescribed Mesalamine suppositories for me to use once a day. Which are quite expensive. The possible side effects are worrisome. I would like to hear from other who have used them and your experience. Thanks!