My experience, and lots of questions

Allergies, blood and immune system
1

Wow, that's amazing! I think (well, I hope) I have a little breakthough. I've been taking B12 injections, folate (since recently) and some other supplements for a while already (I wish I wrote down when I started the injections, sometime in January or February). My weekend days are Friday and Saturday. Ok, Friday out, enjoying a bit of nature. Suddenly I felt like I needed to go to the office to do some overdue work. So I went, and in four hours I did more work than in the whole last week. Again today I did a massive amount of work. My concentration was just there. I haven't felt like this in ... probably years. The tinging in my arm and leg (and tongue sometimes) finally seems to be getting better. It still comes back when I do cardio workouts, but only weakly

- why might that be? The connection to cardio

More than half a year ago I had really big problems with irregular heat beat, which also mostly is gone now. An irregular beat every now and then, but there's no comparison.

I've been wondering: This whole thing started with extreme irregular palpitations and a massive asthma attack. Pernicious anemia can manifest itself with dsypnoe.

- Considering a lung challenge test only showed a 10% reduction and I've had weak lungs as a child already, is it possible that the symptoms of PA can have the appearance of an asthma attack and that the usual bronchodillators and other asthma medications actually do work?

I read that red bloodcells live for about 3 months. Right, when I started with the injections in late January or early February then about half of my red bloodcells were created after I started the therapy, still of course they don't need to be in pristince shape.

- I read that the usual injection therapy is only rather short. The NHS guidelines mention "At first, you will have these injections every other day for two weeks, or until your symptoms have stopped improving." I certainly did not notice any improvement after the first two weeks, and only now would I say there is improvement. I'm still injecting, though only once per week. Based on your experience, would you say the NHS guidelines are actually useful? Are the initial two weeks of injections sufficient to fill up the storage again and to improve on the symptons or is it really better to go on? Have I been overdoing things by still injecting weekly?

Thanks a lot.

2

Hi

I had three injections two weeks ago and,three last week, I'm hoping to last three months now nwxt one 27th may, I do personally think if,we need it,earlier then we should be able to have it. The first week.no improving but this,weekend had loads of energy need to exercise now to get weight off,and feel fitter.

Jules

3

Hi

I cannot answer your questions but I wanted to comment about cardio symptoms. I have been having irregular heartbeats which have got steadily worse for about 2-3 years. They have been really bad, I have had 3 really bad chests, one of which landed me in hospital and I was given inhalers to help.I have been desperate for some answer re the irregular beats, have had the monitor and a cardiac ultrasound or echocardiagram, I don't know which, I was in hospital at the time and not well. I have so many othersymptoms too numerous to go through. Anyway I recently had a FBC which showed low B12. I have had 5 loading doses at weekly intervals, not much change in symptoms, but I have recently bought sublingual B12 nuggets, taking 1 daily, 5000mcg and 1xFolate tabs 400mcg day.I think there might be a link with cardio symptoms, although I haven't read of many people having extreme palpitations. They are so frightening, they really scare me. May I ask, why do you inject when there are sublingual methylcobalamin tabs available, is it better? I am only on the 1st week of my supplementation, I can have another jab at 3 months.I would value your experience about the decline in your palpitations. Are you in the U.K?

Thanks and best wishes.

4

Ha Bigsby,

I think these kind of anemia can cause palpitations as well. It's gotten much better now, even though they are not completely gone. But I stopped being scared. I have a strong heart.

I had cobalamin tablets for quite a while, but they didn't do much/anything. Note: still no checks have been done on the 'why', I don't know if I have an absorption problem. But as I have/had quite bad neurological symptoms and the B12 from injections absorbs more. I cannot get sublinguals here. I read somewhere that from 1000my tablets you absorb about 10my, from 1000my injections it's more like 100-700my, depending on the type you use.