Hi everyone, I drink on average two bottles of wine a day, maybe twice a week I'll only have the one bottle, my husband is also a big drinker but he is 20 years older than me and I dont think he wants to change, I have my first perscription for Selincro which I collect tomorrow, I was just wondering does it work straight away, does t take a few days to build up in your system. Its really hard as Im a hotelier and our hotel is licensed, its not an excuse but it gos with the territory, I would just like to be able to have one maybe two drinks, not two blooming bottles. Any advice welcome, thank you xx
It will have an effect first time you use it, you will probably find that you drink less. But it will take a few days before you notice that your alcohol intake has reduced considerably.
There are some things you need to know which should have been explained by whoever prescribed it for you.
1. You are likely to have some side effects such as nausea and sleep disturbances. Persist with the Selincro, they subside over the first few days as your body gets accustomed to the drug.
2. Selincro works by blocking pleasure receptors, preventing endorphins attaching to those receptors, so that you don't get the same reward from drinking. The problem with this is that other healthier pleasures work by the same release of endorphins. Exercise, extreme sports, rollercoaster rides, certain sweet and spicy foods, sex, cuddling babies and seeing cute animals also give pleasure by the release of endorphins. The Selincro will block the receptors in the same way and you will find that these other activities don't give you the pleasure they used to.
The way to overcome this is to, as soon as you can, start taking days off from drinking, when you won't need to take your Selincro and doing these other activities on those days. As time goes by, as the Selincro reduces your addiction and, eventually, makes it extinct, you will find yourself drinking far less frequently and may end up carrying a pill 'just in case' you drink.
Hi Jodyanne, I just read a post about a herbal remedy called Kudzu. I am going to search here in my town to see if I can locate some.
It is suppose to take away any cravings for alcohol and the lady who sent it says she no longer had these crazy cravings or for smoking as well....sooooo
Good luck to everybody on here.
Thank you Paul, I have had the side effects explained, Im not expecting the first week to be a walk in the park, but whats a week out of our lives... as I said I run a guest house, so work form home, we have no guests in for the next ten days, so If I cant sleep at nights, so be it, I can have a nap during the day or whatever.
I think this an amazing forum and thank you for taking the time to reply to my question, Im sure you have to say the same thing over and over again to new members.
isnt it strange the way our minds work, I keep thinking I better drink as much as I can tonight before I start taking the tablets.....
Thank you once again, Jo
Good luck to you too Tim, let us know how you get on if you start with the Kudzu xx
Hello Jodyanne, I am in excatly the same situation as yourself, drinking two bottles of red a night, I started taking Selinco 8 days ago and have been keeping a blog thing on here of my experiance with the drug. Look at my discussions.
PaulJt1964 is a mine of information and a good bloke to boot, any questions he is the man to ask 
You can do this, the first week wasnt particually nice but I managed to convince people i was just under the weather.
I will follow you to see how you cope, i find with the support of this forum and the good people on it, it s not such a daunting task.
I dont want to stop completely, just reset my desire / need
Good luck
basil
ah thank you so much, I will look at your previous posts.
Its nice to be doing this with some extra support.
Its nice to know I can come on here for help, advice or support.
Paul certainly is a wealth of knowledge and its great hes here to support & advice us.
Thanks again basil
Good luck to you too
Basil, your comment:
"I dont want to stop completely, just reset my desire / need "
This is my goal as well and I have explained that to my cousellor many times over the years. All he (and my GP) could say was - JUST QUIT...
As I mentioned earlier to Jodyanne, there is a herbal remedy called Kudzu that I am going to try. Will let everybody on here know how I make out...
Tim
Like Paul said, Selingro starts working about 1-2 hours after taking it.
You will notice the difference straight away.
However, I don't agree with the expression "some side effects".
The side effects in the first week is strong, very strong.
Now the following, the side effects do wear off and are not stronger than a fix hangover.
Like you I'm working in the hospitality industry (kitchen Chef), our jobs have everything to do with alcohol.
I'm on my 68th pill right now, and my daily intake of alcohol reduced from 28 pints of 8.6% alcohol to 2.
Allready on day one I reduced 20 beers.
The goal you set for yoursellf is for sure acceptable (from two bottles to two glasses)
Just get yoursellf trough the first week.
Does it work, yeah, realy it does.
Good luck,
The only reason I said 'some side-effects' was that not all people get the same ones and I have known people get them so mildly that they are not bothered at all by them. The nausea and sleep disturbance are most common. The side-effects DO seem to be more common than stated by the report of the clinical trials, though.
But even though I seem to be working my way through all the various symtoms 
its still going to be worth it ..
wow thats amazing, well done escargot,, its not an excuse but as you know it is so hard in this industry.
I hope that im prepared for the first week, bring it on, I can beat it...
I know before when I have gone ''cold turkey'' I cant sleep, sweat a lot and become very anxious, Im looking forward to getting through the first week, thanks for taking the time to reply x
I know what you mean, when I did dare metion it to my dr, he said he would refer me to a counsellor and that I shoul attend AA meetings. Good luck Tim x
It' was not ment to be critic towarts you Paul, the only thing is, I experienced a whole lot more than just some side efects.
I felt like my body wad being ripped appart, was sweating like a pigg, felt my heartbeat beating like a base drum sound system etc etc.
The things I felt where not just some side efects, and I strongly feel we should mention those.
Are, when I look back, the side effects worth going trough, then I say yes, they are, the do wear off and Selingro still is, to me, proofed to be effective. (If only you get trough those horible first two weeks)
Oh thats one thing Jodyanne, the side effects I did experienced, could come from detoxing alcohol, and maybe have nothing to do with Selingro itsellf.
We'll find out, don't we.
Keep us updated, the more posts the better ;-)
Hi Jodyanne
I feel the same way ( as i have done ) for the last 3 weeks; in regards to '' my last drink so what the hell'' as well. i was supposed to pick up my prescription for nalmefene today but unfortunately '' the '' letter from Acorn hadnt arrived ; after i had phoned up and got the perfect time for an appointment ;4.10. Its a journey in itself to actually get this stuff. VERY interested to hear how you get on with it , Best Wishes
No, I know it wasn't a criticism, Escargot I agreed with what you said and wanted to clarify what i had said
Hi there, I posted on here last night with the same problem, although I dont drink everyday, when I do drink, i cant stop. How does selincro work? Does it keep you sober so you think "whats the point, I might as well have a cuppa" or does it make you ill/vomit when drinking on it? I think it would suit me if I popped one say on a Saturday night, so would be no point in drinking.
I am just starting week 4. The first two weeks were really awful. Be prepared ! Everyone is different of-course but if you are able, treat yourself as if you have flu. Be kind to yourself and relax as much as you can. Its worth it....IT WORKS ! I have gone from 1 to 2 bottles a night to 3 glasses.
I found it worked fairly quickly. Beast of good luck !!
Good luck to you to Michael, hope you get it soon and post how you get on x