Peripheral neuropathic pain, sometimes unbearable

Brain and nerves
1

Hello,

I suffer from increasing nerve pain, started from the big toes in both

feet, then during 5 years spread unto lower legs and even started

in the hands now. It is the "tight sock" feeling constantly plus

needle feeling and electric shocks sometimes.

Only Tramol plus Gaba gives some relief, but i maxed out on this

medications.

Can anybody recommend other drugs or supplements ?

Thank you, Chris

2

I'm waiting for my go to ring me I've tried so many different meds getting fed up now as pain is so severe I can't even sleep will let u know how I get on best wishes

3

I have Autonomic Polyneuropathy. I had an below knee amputation, also on my right foot, I only have a half foot. Even though they are gone, I still suffer from the pain and burning. It's in my hands and arms, back and breasts as well. I was on neurontin, but gained weight. I now take lyrica and oxcycontin, dilauded. An anti depressant, and roprinerol for restless legs. Not from diabetes. I have a cluster of auto immune diseases, and had a bone infection that resulted in the amputations. Through the years, I've been on many meds. Basically trial and error! I'm a 52 years old female

4

Hi chris

I have recently developed tingling then burning in my hands and

feet and I am having tests at the moment to try and find out the

cause. I've tried various drugs, probably not trying them for long

enough, but have been taking Mirtazapine at night for the last

few weeks. I started on 15mg and now upped the dose to 30mg.

I have to say that I haven't felt significantly better on the higher

dose but I do get a good nights sleep. On the Mirtazapine forum

there are many mixed opinions of this medication but of course

everyone is different.

I hope you find something to give you relief. Best wishes.

5

Hi Chris I'm so sorry for your pain, but I sure do understand. I'm also maxed out on gabapentin. I'm going to be trying to switch over to Lyrica very soon. I've also had lts of epidural steroid injections in different parts of my back to try and help with pain. Some have worked, some haven't. I've also been given a pamphlet about a spinal chord stimulator that is implanted gor pain relief. Are you a diabetic? What tests have you had done? Be hopeful Chris, I know it's hard!

6

Have you tried lyrica or cymbalta I couldn't take either one but everyone is different

7

Thanks Judy, i am trying Lyrica now - it seems to have the same positive effect as Gaba.

I will check out cymbalta, thanks for idea !

8

Hello Mari,

thamks for your answer - i tested negative for diabetes, i assume my

former contact to pestcides may be the cause.

I'm trying lyrica now, it seems to work in quite high dosage. Since this med is not covered by my insurance

it's a costly enterprise.

I dont know about spinal cord stimulation, i had a lumbar operation

because i hoped it would solve the problem but it didnt.

In your case i would first try electric stimulation on the skin along

the nerve routes - i ordered an affordable machine from ebay and will try this

out soon.

Thanks again and let me know about your progress.

9

Hello Woodie,

it's a consolation to hear i'm not alone with this problem.

I also have troubles sleeping, i'm using anti histamine for that - works fine but

timing is critical. If i take it in the late evening, the effect lasts

too long and its hard to get up the next morning.

Thanks for your idea, i will check it out.

10

Hi Liz,

wow your symptoms look even more severe than mine.

I understand you went through a lot of pain and troubles.

That makes me a bit more humble - i also pondered sometimes

if this neuropathy could be an autoimmune disease.

That would need trearment with alfa interferon - but my doc

doesnt agree, so i didnt get it prescribed.

So i wish you also success and pray for you.

11

How is the lyrica working out for you? Any nasty side effects? I hope I can take it with no problems (I don't mesh well with most meds). I'm not a diabetic either, and the neuropathy is one of my biggest problems. It seems to be progressing so darn fast. Are you having any issues with dry eye or mouth? I recently had a lip biopsy to see if all of the crap is from Sjogren's.

Do you ever have places on your body that randomly get really hot , or do you wake up at night with the neuropathy pain in your arms and hands? I know we have to stay hopeful. I'm guessing you got a Tens unit. Let me know how that works out!

12

Hi Marie,

yes thats exactly my feeling - i get tired to try many different

meds and treatments, I'm trying acupuncture now, until now no effect.

I recommend to you to try antihistamine for sleeping.

Also massive amounts of Vit. B complex and Vit. C ( i use about 3 g

of Vit. C each day) - has no immediate effect but longterm i got the feeling it reliefs

the general condition.

For the pain, Tramol plus gabapentin / pregabalin works for me,

please try to convince your doc to prescribe. Tramol can be

critical for some ppl, it causes constipation and loss of

appatite (what is good in my case, i lost 8 kg).

Hope that helps you a bit, i understand your frustration and pray for you.

13

hi Chris gp has just upped my meds today still awake here with burning pain in feet upped gabapentin and prescribed tramadol not working at the mo did u say tramadol made u lose weight best wishes

14

I was given amatripaline to help me sleep because I hurt so much and could not sleep

15

hi Judy I suffer real bad I've had every tablet going I'm waiting for this tramadol to work at the moment can I ask what has happened to u hun

16

I have Cemo induced nurapathy I had Hodgkin lymphoma when I was 26 I am now 46 my legs have been real bad last two years like you they have tried everything to help I take norco for psi it helps now that I take them four times a day

17

I Ment when I was 16 I have burning and stabbing pains I I have places that are getting numb I stumble sometimes this stuff is awful

18

Hi Marie

I wondered if you get sudden hot sweats. These can come on

for no apparent reason such as when I am sitting reading. 

Last week when it was hot it was absolutely awful.

19

I do get hit sweats hun but not sure if it's the menopause

20

Hi. I don't get hot sweats like that very often. Sometimes at night I will wake up feeling like my core body temp is really hot and I will be really sweaty around my chest area. Once in awhile I will get a sensation of being overly hot but I won't be sweating a drop. Do you have a problem being out in the heat also?