These notes are copied from a research on how ursodeoxycholic acid or a mixture of chenodeoxycholic acid can help with GB function to normal. Any one who want to remove the GB, should try this for 5 to 6 months and decide if you want to remove gb or not .
Research results:
In total, 275 patients received DISIDA scans from March 2012 to May 2016. Seven patients were excluded because they were less than 18 years old. Four patients were excluded from the analysis because of poor medical records. Another 192 patients were excluded because they had an organic cause for the symptoms or abnormal laboratory test results. The organic causes included gallstones, sludge in the GB, GB polyps, GB adenomyomatosis, malignancy of the GB or bile duct, cholecystitis or cholangitis, pancreatitis, peptic ulcer disease, and reflux esophagitis. Fifty-three patients were excluded because their symptoms were acute or episodic, in the right upper quadrant or other abdominal locations, or they had symptoms inappropriate for FD. Another one patient was excluded due to insufficient symptom duration (<2 months) for the Rome IV criteria, although other conditions met the criteria (Fig. 2).[Figure 2]Figure 2
Finally, 18 patients had symptoms compatible with the Rome IV criteria for diagnosing FD and all corresponded to RFD (Table 1). Of these, 10 had epigastric pain syndrome (EPS, a subgroup of FD; epigastric pain, and/or epigastric burning), 3 had postprandial distress syndrome (PDS, the other subgroup of FD; postprandial fullness and/or early satiation), and the other 5 had both epigastric pain and postprandial fullness (overlap). Three of these patients did not revisit our hospital after undergoing the initial DISIDA scan (lost to follow-up); 2 of those had normal GB function and the other had GB dyskinesia. Of the remaining 15 patients whose symptoms met the FD criteria, 8 had normal GB function according to the initial DISIDA scan, so no follow-up DISIDA scan was performed. GB dyskinesia was demonstrated on the initial DISIDA scan in the other 7 patients. We prescribed 1 or 2 choleretic and litholytic drugs, such as ursodeoxycholic acid, Rowachol (terpene mixture), or a mixture of chenodeoxycholic acid and ursodeoxycholic acid for all 7 patients with GB dyskinesia. Mean duration from the initial DISIDA scan to the follow-up DISIDA scan was 5.6 months. The symptoms of 4 of these 7 patients disappeared after GB function normalized at the follow-up DISIDA scan. The symptoms of 1 of them disappeared despite persistent GB dyskinesia at the follow-up DISIDA scan. Symptoms and GB dyskinesia persisted at the follow-up DISIDA scan in another one patient. None of the patients had persistent symptoms despite normalization of GB dyskinesia at the follow-up DISIDA scan. The other one patient in whom the symptoms disappeared refused to undergo a follow-up DISIDA scan, so GB function when symptoms disappeared was unknown. Hence, FD symptoms were demonstrated to be caused by GB dyskinesia in 4 of 18 patients (Fig. 3).