Primary antibody deficiencies (PADs) are the most common primary immunodeficiency diseases. They are a diverse group of disorders which are characterised by various degrees of dysfunctional antibody production because of disruption of B-cell differentiation. There is often a significant delay in reaching a diagnosis of PAD, leading to an increase in morbidity and mortality.1
This is a companion discussion topic for the original article at https://patient.info/doctor/paediatrics/primary-antibody-deficiency