I was hesitant to post my discovery of SAM-e here, but if I can help one person, it will have been worth it. I have been on 30mgs of Citalopram for 12 weeks. I still struggle with low moods and was getting desperate. It was only when my wife asked me to call a Naturopath that everything changed. It told her I knew what the ND would suggest, SAM-e. That same day, now five days ago, I went to purchase a ten day supply to see if it could be a good add-on to my AD. I can honestly say that I am doing so much better having added 800 mgs of stable SAM-e to my regimen. It has t be taken upon awakening on an empty stomach and food must be avoided for at least 30 minutes therafter. For SAM-e to work even more efficiently, a B-Complex should be taken at meals. This is not my forst go around with SAM-e as I studied alternative health for approximately 30 years. My advice is to do your own research and determine if it is a good fit for you. Those who are in the early stages of Citalopram and wish to see results sooner, SAM-e is known to be effective in days and not weeks or months. It is on the pricey side because it is sourced from Italy and must be enteric coated to protect the active ingredient from stomach acid. If anyone would like to know more about SAM-e, please don’t hesitate to ask me. The brands that are recommended are Nature Made and Doctor’s Best as both source from the same place in Italy. I am feeling better with each passing day and can only see blue skys ahead thanks to this marvel that promotes not only mood enhancement, but joint pain and liver health. Don’t forget the B-Complex.