I just wanted to add my comments to everyone that has posted under this title and to answer questions left by some.
I have been on Sertraline for nearly 2 years now and it has completely changed my life. I too could not switch off my brain and frequently told people that I just need to be able to take my brain out and put in a jar until I've had a break from it! I thought everyone was like that.
I have always been an analytical thinker even from being a small girl but when I got older and lifes usual stresses and strains come into play my brain would go into overdrive. The scenarios of \"what if...\" would torment me for hours and hours until eventually (and this is the only way I can describe it) I burnt out!
At this point, my doctor put me on 50mg of Sertraline. I was not given these drugs for depression, it was to just try and give me a break. I have obsessive compulsive thoughts, not behaviour, on really bad days I did used to obsessively check things but not to any significant degree, it was always about my thoughts. I felt the side effects within 4 hours of taking the medication but this could be because I am small. They lasted for about a week and I had double vision, sweating, sickness, no concentration, short term memory loss and feelings like I was zinging. However, I persevered and the side effects did go.
In response to another posting, yes, I have put on a little weight since being on these tablets, but that was something else I was obsessed about but since being on these tablets I am alot kinder to myself about that too. It took time for my weight to regulate and I think it has settled down now.
After a year I felt so much better so I thought I would try and live without them so with the support of my doctor I started reducing the dose, and I did not get withdrawal effects, but unfortunately, after time I started getting the same old feelings of \"what if...\" so was advised to increase my dose to every other day again.
I guess what I wanted to say was that this particular drug has worked for me. I have obsessive compulsive thoughts, always have, and realise I always will. But these tablets have given me peace. I am peacefully happy, calmer, more positive and in control. It is particularly difficult to constantly be living inside your non stop \"what if...\" brain, so if this allows me to have a fulfilled life then so be it.
Good luck to everyone who is just getting on these tablets and I truly hope that they bring as much peace to you as they have to me.