In people with migraine it is thought that some chemicals in the brain increase in activity. As a result, parts of the brain send out confused signals and this results in the symptoms of headache and sickness. Why people with migraine should develop these chemical changes is not clear and many migraine attacks occur for no apparent reason. For some people, there may be things which trigger an attack, like certain foods or drinks.
This is a companion discussion topic for the original article at https://patient.info/medicine/tolfenamic-acid-for-migraine-clotam-rapid