weight gain and Methotrexate

Thank you for your answer... You've been living with RA for 10 years. Are you able to go to work? I won't be able to afford my medical bills if I don't work

oh yes, I live on a farm and ride horses regularly. I am 67

I've been using methotrexate 20mg a week for the last 10 weeks and have noticed a slight weight gain I feel I should of lost weight as I've cut out alchol obviously and usually when I did In the past I'd lose alot more. It's like my body is tipping slightly more to the fat side of things but not overly too much. I've and autoamune disease, uveitis (6 years) so dunno if that's anything to do with it.I've also been on pred forte for the last 6 years to without fail. Anyone else out there with similar eye problems. ???

When my RA was really active I was losing weight. started Mtx 7 months ago and am gaining weight. My eating never changed and I don't eat a lot. Will go back to no carbs and see if I can shed thes pounds!  At least I don't feel crazy- nothing on the side effects talks about weight gain!!!

 

I've gained 3 stone!  I'm due to start Otezla (a recent biosimilar drug for psoriatic arthritis instead of an anti-TNF) which has a side effect of weight loss - I live in hope!

Hi, I started with pills and lost a bit of weight but went up to injections (20/week) and started gaining, we switched to injections because the side effects were horrible, then I (working in the health field) discovered a trial where Oil of Oregano(has to be 80% carcavrol min) used in mice on chemo reduced liver toxicity, and I know they sell it for humans for colds etc and it does help with UTI'a so I tried it... and low and behold I lost the weight, the headaches and muscle aches I was getting on day 2 after the injection are almost gone and I am not catching every little sniffle that passes! There is not a single other natural remedy out there that I would think twice about, but this, It's definitely worth trying.

Hi carrieann I started mtx six weeks ago and I can not loss weigh. I only take 15mg at the mo once a week. I eat less and still stay same.

Bel35

I was diagnosed with ra over 2 years now I am on maximum does of 25mg of methotrexate also folic acid I have gained over 3 stone and I am taking really bad with it. I do eat sensibly salads, veg , fish fruit . I have always been around 9.5 - 10 stone I am now nearing 12.5 . My doctors also say there should be no weight gain which is clearly not the case . Hearing others are gaining weight now makes it more clearer to me it is the methotrexate at fault .

I was diagnosed with RA, Lupus & Fibro all around the same time. I take a handful of meds 3 times a day and Metho on Wed nights. I've heard horror stories about hair loss, weight gain and no alcohol. Also I've heard a lot about liver damage. My Doc say NO ALCOHOL PERIOD.

This is life changing for me because I am used to going to social events that revolve around alcohol. I feel like the only normal part if my life is gone now. It's bed enough to be disabled by these diseases but now what was left if my "social" existence had been taken away. I'm a YOUNG 50 y/o woman and had a social life but now that I can't have cocktails...no more brunches, girls nights...just nothing. Im left feeling like a hermit and wonder why I should even get out of bed at times. Alcohol was a major part of my social life. I can have fun without it but I really enjoy the time when I can go out & let my hair down. #Depressed

Could be related to not drinking alcohol. I haven't had a drink since 2 weeks prior to starting MTX. I eat 1 meal a day but I've noticed that my jeans are a bit snug lately. Even without alcohol, and eating the same portions. But I can't est st all the day after I take the MTX. I take it on Wed nights so I will be well by the weekend.Supposedly....

Hi im on 20mg Methatrexate and was told no alcohol but like you I have a social life that evolves around good friends and alcohol.. (I'm 51) I havent given up alcohol because didn't want to lose that side of my life and I am totally fine!!! I have liver function tests done monthly and all come back healthy.. So a little of what you fancy in my eyes is good for you and your mental well being!!! Don't suffer and be miserable 😃

I was diagnosed with PA 2 years ago. I continue drinking, usuallly only friday and saturday and no more than 8 beers per week.

And all my blood test has been good. I always told my doctor that I only drink 2 drinks per week.

So you can drink a little and see how you feel and how your blood test goes. Do not be depressed. Cheer up!!!

I too thought I should lose weight which I was looking forward to after being on prdnisone for 3 months.  I've been on metholtrexate now or about the same amount of time low dose 10 mg a week and my stomach is huge.  I take folic acid daily (when I don't forget).  Will have to stop taking methotrexate for a few weeks now because of low WBC.  I robably won't go back on it.  Either the folic acid or meth causes me headaches and I don't know that it's doing much for for my arthritis --- back to the drawing board I guess.  Thanks to all who posted about the weight gain.  I wondered what was going on.

I've lost weight too! Only 4kg in about 8 wks since I've started. Taking prednisolone twice daily to manage. I have PsA. Can't imagine it's too healthy but the doctor says it's nothing to worry about yet.

I also gained about 10 lbs. which is impossible to lose.  Very upsetting.

Sadly, yes this has been a side effect for me and I've only taken 2 doses (20mg). I don't have any nausea.

I am on Methotrexate for the past three years and have gained about 12lbs, I gained this weight almost as soon as I started taking the drug but have managed to not gain anymore weight.

I find it almost impossible to loose any of the 12lbs I gained no matter how much I exercise or how little I eat. I hope that once I get off the drug I will loose the 12lbs.

thanks

Did you lose weight because you started taking Oil of Oregano(has to be 80% carcavrol min)? Or is it because you started taking Oil of Oregano(has to be 80% carcavrol min) and was able to stop the methotrexate?

Just now finding this & very curious if acupuncture is still enough treatment for you.?? Recently attempting same - no MTx in 6 months started accupuntire 3 mo ago but don't know anyone else trying this.

Thank you in advance for any input.

I have lupus, RA, Fibro, and many other autoimmune issues too! I have just been bumped up to 25 mg, and lowered the prednisone to 3mg. I used to be on 80mg of prednisone, and was in bad shape and have the scars to prove it. The prednisone is the weight gainer, along with some others like the Gabapenton. I am on a lot of medications for my issues, and am being watched constantly. (Around 50 pills a day) But this is no reason why you can't have fun! There are many things I can't do like I used to, but I can be in control if how I think of things! God is my center, along with his son Jesus! Through my strength I have helped others through there issues, and I will help all of you too!

No matter what happens to this body we have, it's God's promise that gets me through each and every day! He will make us whole again, maybe not while we are here; but he will do so! Remember that Jesus took our burdens, so, we can live in freedom! Freedom of hurt, pain, suffering, and sin. But we must die with this body first, to be reborn in him! That is where you can find your strength to get through the hard times!

Alcohol is and evil prison, that makes people believe they need it, along with other evils of the world. In the Bible, it tells us to stay alert and sober minded. We can't do that if we are filling it with unnecessary toxins. Yes, we may need these meds to get through these days on earth, but later with faith; we won't need them! We will be whole again!

Give your burdens to Jesus, he suffered so, we would not need too. The world will hate us, just as it did him; but we will not be forgotten! He loves you, as our Father God does. We were never meant to have disease. Human sin did that, and that is why our body must die; to receive our new body. Without sin!

We must love and help each other, that is why, he has led me to all of you! I want you all to know, that no matter how much our bodies attack us, we must not loose our faith, love, and compassion! Do not let evil take you over to depression, or other forms of drowning our sorrows! We cannot afford to loose our soul too!

I have many wounds, sores, and scars that wont go away. Pain that prevents me from doing things I used to do. But with the help of our Father and his son Jesus, we will find new things to take there place! Every time a door closes, a new one always opens! You just need to look and listen, and ask God for help; and be willing to receive the help! He gives it to you in all forms!

I hope this helps you, and others like us! Peace be with you ALL! You will be in My prayers! Keep loveing!