which shot hurts the worst?

I was so glad to get on Xeljanx XR because I didn't have to take shots. I've taken humira and Enbrel. Enbrel hurt like hell so my husband gave them to me. I am starting to get the feeling that Xeljanx is not working like it did when I started it so if I have to take shots I don't want one that hurts like Enbrel.

Have you tried getting the numbing cream from the pharmacy for about 5 pounds it can make the shops feel better

I was told to put Embrel in my thigh..... God No Way. After twice being in agony, I grabbed a couple of inches of tummy fat and put it in there. I have painless injections every week for 9 years now. I just alternate sides each week. Hope this helps. X

I found Cimzia injections very painful, in tears almost every time. Now I have Benepali and also inject in my tummy

​alternating sides, sometimes hurts but not every time. In the thigh was agony and I also bled a lot, will find out about the numbing cream as it sounds like a good idea.

I have been on Humara for over two years.  I leave it out to room temperature so it stings less.  My daughter gives them to me and it does sting for a few seconds.  I also alternate the sides of the stomach.  If we can stand the RA pain the shot is a breeze.

That is what my rheumy wanted me to take. AHHHHHH! I'll have to ask her about Benepali.

Thanks to everyone's advice. Sounds like I will have to get some numbing cream and have it on hand if I have to go back to shots. I am not giving up on Xeljanx yet. I'm having horrible pain from lower back problems and I think it is aggravating my RA. If I can get the back pain under control maybe....

I don’t think the shot or needle hurts but the medicine going in stings but not that terrible.  Everyone has a different pain tolerance.  Good luck.