I've been suffering with severe lower abdominal pain and constipation for years but its been much worse over the past few months. Ater numerous tests my GI ordered a lactulose breath test which was positive for methane. I'vw had two rounds of xifaxan both of which helped for a short time. Then I followed the low Fodmap diet for 12 weeks During that time the pain and constipation returned. My GI has now prescribed Xifaxan and neomycin. I wondering if anyone here has used that combination. If so were there side effects? Did it help? What was your dosage and for how long. I am concerned about side effects because I have difficuty tolerating meds. My GI said they are not absorbed and stay in the intestines so are usually well tolerated. Thanks for listening.
J Clin Gastroenterol. 2010 Sep;44(8):547-50. doi: 10.1097/MCG.0b013e3181c64c90.A combination of rifaximin and neomycin is most effective in treating irritable bowel syndrome patients with methane on lactulose breath test.
Not something I have come across.
Helen,
Where are you based?
This combination has been tried various times, mainly in the states as I'm pretty sure, Rifaximin isnt available in the UK.