The first benzodiazepine was marketed in 1959. It was described as a 'minor tranquilliser' and an alternative to barbiturates. Benzodiazepines act by enhancing the effect of gamma-aminobutyric acid on the GABA-A receptor, thereby resulting in CNS depression.1 They are anxiolytic, hypnotic, anticonvulsant and muscle relaxants. They also cause psychomotor retardation.
This is a companion discussion topic for the original article at https://patient.info/doctor/mental-health/benzodiazepine-dependence