Ich nehme derzeit 2x37,5 mg (eine morgens, eine abends) ein und werde bald auf die ER-Formel umsteigen, gleiche Tagesdosis. Ist es besser, die gesamten 75 mg auf einmal (d. h. morgens) einzunehmen oder eine morgens und eine abends einzunehmen.
Danke!!
Ich hatte diese Option nie. Ich nahm immer 75 mg gegen 20:30 Uhr. Das war eine Zeit, zu der ich konsequent sein konnte, da ich nicht jeden Morgen zur gleichen Zeit aufstand.
I would like to point out that taking 37.5 mg in the morning and in the evening equals 37.5mg not 75mg. This is due to the drug's half-life...which is why you take it in two doses - to maintain more consistent levels...of 37.5 throughout the day. Moving to 75 extended release will mean you are doubling up the dose as well as changing release...
Was this advised by an actual psychiatrist or a GP? If latter ask them to first up your dose by adding one more pill of 37.5 to your morning dose for a week or so BEFORE switching to 75mg extended release so you can ease yourself into the 75mg therapeutic dose with a shorter half-life first.
This is how my neuropsychiatrist proceeded and how most people I know are switched from immediate to extended release. Doing it the way you plan to may be a little bit of a shock to the system if you are sensitive.
If you were simply moving from 37.5 extended release to 75 mg extended release this would be less of a concern.
To answer your specific query - extended release capsules are taken ONCE per day and this should be done in the morning or no later than lunchtime. Otherwise they can mess with the quality of your sleep.
Kathi, vielen Dank!
Purpledob, vielen Dank für diese großartige Antwort! Ich gehe zu einem Hausarzt, und er hat mir empfohlen, meine Ven-Dosis von 150 mg/Tag auf 75 mg/Tag zu reduzieren und hoffentlich später noch weiter. Ich bin in den letzten Monaten von 150 mg auf 112,5 mg mit Standard-Release-Tabletten heruntergekommen, mit ein paar Rückschlägen, aber es ging okay.
Jetzt möchte ich 75 mg/Tag versuchen und habe hier im Forum schon oft gelesen, dass die ER-Kapseln effektiver sind. (stimmt das?). Er hat mir 37,5 mg ER-Kapseln verschrieben, damit ich die Flexibilität habe, weiter herunterzufahren, wenn ich kann. Meine Fragen sind derzeit: (1) Sollte ich zwei 37,5 mg auf einmal nehmen und (2) wenn ja, wann ist der beste Zeitpunkt, um sie einzunehmen?
Hoffe, das macht Sinn!
Danke fürs Zuhören!!
Hi
ah so you are reducing. Then it is less of a concern. Extended release keeps steadier levels throughout the day which for you, practically, means fewer ups and downs and less tension.
Since you have ER caps at 37.5 you would need to take them at the same time in the morning or latest at noon.
There is a great way of reducing by combining ER with IR release but that may not be necessary at this point since you already did the hard work on IR alone
Take your time when you go on 75 and wait for a couple of months AFTER any adjustment disturbances subside before attempting the next cut to one 37.5 ER.
Good luck
BTW If you were last on 112.5 Immediate Release and taking one 75 IR morning and one in the evening - you are already on 75mg NOT 112.5.
Then by taking 2x 37.5 in the morning you are going through consolidation of 75mg and after 2-3 months dropping to 37.5 should be good. Reduces your chances for a relapse after stopping as well. It is worth it. Basically the longer you take between dose changes the better. I took between 3-9 months between each drop. From 150. No issues, no relapse 4 years - clean.
Wish the same for you.
Purpledob, ich bin SO dankbar für diese hochkompetenten Antworten und besonders für deine ermutigenden Worte, dass man eine vollständige Beendigung erreichen kann. Ich freue mich wirklich auf dieses nächste Kapitel.
Vielen Dank!😊😊😊
Purpledob, ich hoffe, ich gehe mit meinen Dosierungsdetails nicht zu sehr in die Details, aber hier ist der Überblick über meine jüngste Vergangenheit:
15. Aug 16 - 14. Juli 17 1x150ER Kapsel (signifikanter Panikanfall Anfang August)
15. Juli 17 - 20. Juli 17 2x56,25mg IR-Tablette (morgens/abends) *
21. Juli 17 - 30. Sept 17 2x37,5mg IR-Tablette (morgens/abends) * (versucht, die Dosis zu reduzieren)
1. Okt - aktuell 2x56,25mg IR-Tablette (morgens/abends) *
* "Pillen-Schneider" verwendet, um die angegebenen Dosierungen zu erhalten!
Wenn ich Sie richtig verstehe, waren meine "effektiven Dosierungen" ab Juli nur die Hälfte von dem, was ich dachte. Wenn das so ist, ist das eine gute Nachricht, da ich mich einigermaßen gut zurechtfinde, auch wenn es nicht großartig ist!
Jetzt muss ich entscheiden, ob ich morgens eine oder zwei 37,5 ER-Kapseln einnehmen soll.
Vielen Dank, dass Sie zugehört haben.
Cheers
Yes your dose is considered lower than you thought. Not exactly half but not far from it either due to the rebalancing and recoiling that the brain goes through when treated with IR...especially for anxiety disorder.
Ah...word of warning - You were on therapeutic dose of 150 ER less than one full year. 2 is minimum...4 is much better. (2 for therapy and 2 for maintenance).
You were then switched to immediate release (Only a GP could muck this up like that...) and dropped to 56.25 IR x 2 ...erm...technically close to half initial dose and with a nice spike-dip-spike-dip pattern that IR offers. Not great. FOR ONLY 5 DAYS before rushing down to 37.5 x 2 IR. Of course you are not feeling great LOL. Two.Take two 37.5 ER and stick on them for at least 3 months and I would suggest longer to help your brain recalibrate and pick a good equilibrium to work from moving forward. Do not make the next cut in case of any major life changes, illness or extra stress. Pick a good time for your next cut. Take 2 not one. You may be shooting yourself in the foot otherwise. You are already compromised by that reckless drop. Feel free to consult a psychiatrist for a second opinion if you are unsure. But not a GP.
What should have been done, if IR was to be used as a transition, was to take you down to 112.5 ER for a few months and then introduce 75 ER Plus 37.5 IR (taken together or a few hours apart) to train the brain to dip after 6 hours (IR is fast acting). That way you would gradually adjust to the dip before moving to 75 ER which should be kept for a few months. Then the same as above applied by using 1 x 37.5 ER plus 37.5 IR to retrace the dipping procedure for the brain. Then down to 37.5 ER for a few months and finally down to two 37.5 IR if necessary to further slow down. I was fine without that last step. But then I was treated for 4 years PLUS 2 years maintenance and took 2 years to wean off as described.
I went off twice prior to this and each premature and speedier drop landed me back with a vengeance a few months later. So the final lap of therapy was slow and very carefully designed by my amazing neuropsychiatrist. I was treated for massive GAD. The second relapse triggered transient psychotic episodes...So I was in no rush in the final lap. Slow does it.
Let us know how it goes whatever you decide.
All the best
Ich finde keine Worte, um Ihnen zu sagen, wie sehr ich diesen kompetenten und tröstlichen Rat zu schätzen weiß!
Ich habe mich selbst entschieden, eine vier Tage dauernde Reduktion auszuprobieren. Reine Unwissenheit meinerseits. Mein Hausarzt ist ein guter Arzt, aber er hat mir im Wesentlichen empfohlen, von 150 mg/Tag auf 75 mg/Tag zu reduzieren, ohne spezifische Angaben zu Zeiträumen usw.
Im Nachhinein hätte ich wahrscheinlich eine Überweisung an einen Fachmann anfordern sollen.
Ich fühle mich sehr wohl mit Ihren Empfehlungen für die Zukunft. Ich führe sehr detaillierte tägliche Aufzeichnungen über meine Angstlevel und Schlafqualität und werde gespannt sein, wie der Übergang zu den ER-Kapseln verläuft.
Es ist erstaunlich für mich, wie tröstlich es ist, eine kompetente Person an meiner Seite zu haben. Ich fühle mich, als hätte ich einen Vorsprung für die nächste Phase😊
Wenn es Ihnen nichts ausmacht, werde ich Ihnen später einen Statusbericht schicken.
Prost
Hi I'm back again.
I've been talking one bead from my 150mg out for one month and I wake up feeling awful. I've started with two beads less now in 2nd MTH but starting already to lose faith. Don't know if it's already part of withdrawal or what. As I said before I've tried many times to come off with help of dr's was fine for few mths then crashed. So trying on my own. Reasons for wanting are been on it for many years don't feel it's helpful and only recently realize that it must be this medication that's caused my weight gain.
In an awful state!
Can anyone help? Please!
Hi. Would you like to list your history on this drug in some detail?
When did you start?
What symptoms caused you to be prescribed this?
When was the last time you tried to properly come off with doctor's help and how was the taper designed?
How soon after removing just one bead did your condition start to worsen in your opinion?
Were you ever well on this drug?
Were higher doses ever attempted?
Were you ever on any other psychotropic drugs before or after starting venlafaxine?
Any details will help.
See, the problem is, that if you are tapering before actually being well on the drug, you are not likely to fare well however slowly you withdraw. The brain has nothing to draw on or reference to function optimally. Apprehension about impending crash makes you immediately stressed so you end up nowhere.
Have the doctors not suggested a bridge, such as Prozac, to aid in the taper? Have they not advised trying a different dosage? A different drug or combo?
x
I've come down from 150mg daily to 37.5mg per day, after 2 year's use. The effects the past few weeks have been horrendous, suicidal, anger, frustration, depression, anxiety, tearful, dizzy spells. I hate this medication have been trying for several months to get off this nasty drug. Got down to 16mg but the effects were so bad had to go up again, now waiting to see a Psychiatrist for help to get off them for good
Hi my doc wants me to change from 37.5mg immediate release at night to 75mg extended release at nite is there any side effects
Hi did u have any side effects?