Chronic myeloid leukaemia (CML) is a myeloproliferative disorder of pluripotent haemopoietic stem cells, affecting one or all cell lines (erythroid, platelet and myeloid). Over time, the leukaemic cells proliferate due to stepped-up production and failed apoptosis. More than 90% of cases of CML result from a cytogenetic aberration known as the Philadelphia chromosome. CML typically progresses through three stages:1 2
This is a companion discussion topic for the original article at https://patient.info/doctor/oncology/chronic-myeloid-leukaemia-pro