I had PHPT and was cured in Tampa

Hello

I just found this forum today and have read some of the posts.

I would like to share my story in the hope that it helps.

I am in the UK (I used to work for the NHS for 11 years until I got PHPT and was so ill I had to give up my job).

I had PHPT for at least 6 years before I found out what I had.  It mainly affects postmenopausal women and I thought the start of my symptoms were menopausal as some were similar.  Long story short, even though my Rheumatologist said I was "really too young", she diagnosed me with Polymyalgia Rheumatica and gave me steroids for a year (Prednisolone).  My GP gave me Calcichew and Vit D, and Omeprazole to cover the Pred.

But I eventually found out I had high calcium and high PTH and that I had PHPT - I had been diagnosed, and was being treated for, the wrong disease!  Being on the steroids was terrible - it masked the pain a bit but had horrible side-effects including the awful weight gain.  When my GP said she didn't know why my calcium was high, I researched it on the web.  I was aware of PHPT from working in the surgery (I was an administrator), but didn't realise at that time that's what I had.

Long story short I sent my results to the famous clinic in Tampa who confirmed that I had PHPT and 3 weeks later I went to have my adenoma removed.

The staff and the treatment and place were absolutely fantastic and absolutely first class.  Everything that took place was just as it states on their website so there were no shocks or surprises, and the whole process went like clockwork.

My operation was carried out with a local anaesthetic in less than 20-30 mins.  I have to say that I was one of the 20% of people for whom my tumour was NOT in the usual place behind the thyroid gland.  It was buried deep in my thymus gland and had to be bisected.  This tumour did NOT show up on their Sestamibi scan but their Sestamibi scans in not showing where the tumour is, can show where the tumour IS NOT i.e. it will show whether there is one in the chest near the heart and the thymus gland is at the top of the chest.  They knew roughly where it would be and the gamma probe confirmed it.

The simple truth is that they are state-of-the-art, do only this operation and have perfected it over many years and are very experienced and I know with absolute certainty that the tumour in my thymus (the size of an olive) would not have been found in the UK and I refused an NHS scan and trusted Dr Norman at the Tampa Clinic to find where it was. It was the BEST thing I have ever done, I had been very sick for years and the sadly wrong diagnosis and treatment I got over here made my osteopenia even worse (when you have a parathyroid tumour, taking calcium and Vit D doesn't help - it just makes things much worse which it did in my case and could have caused a stroke or heart attack. In fact I did develop heart palpitations before going to Tampa. 

Bottom line - sadly the NHS here and the private consultants (usually the same ones doing the NHS operations) - are not yet as advanced and far forward with parathyroid operations (no disrespect to them) as the clinic in Tampa. Over here they still work the way they were taught at medical school years ago and don't truly understand how this disease works.  A lot of them think a low Vit D causes high calcium when in fact this is impossible - the body suppresses Vitamin D in the presence of a tumour by way of a protective measure and patients are often given big doses of Vit D which just makes you feel worse.

The Tampa clinic also have the benefit of the gamma probe which they invented which also helps to locate the tumours as it makes a loud buzzing noise when the probe is near a tumour.

Even doing the operation privately here is not the same as Tampa.  I am aware that the surgeon in my area has tried to purchase a gamma probe but the NHS refused funding.   The Tampa clinic has a virtual 100% success rate and the operation, not done with a General Anaesthetic and with only a 1" cut, is so much less traumatic for the patients.  I left the clinic 1-2 hours later and was fine.  I did have quite a bit of bruising and some swelling but it wasn't painful I didn't need any painkillers and they give you an ice bag and calcium to take with you which really helped.  Had my tumour been in the usual place behind the thyroid, there would have been less bruising.  I cannot recommend them highly enough.  I could go on but my info is long - sorry, but I feel so sorry for all of you who are still suffering especially when there is a cure in Tampa and the wait for an op is just a few weeks once diagnosed.  I really felt so ill by the time I got there, I had a headache and high BP on the day of my op, and now, 2.5 years later, I am soooo much better, not quite 100% but getting there (the steroids took even more calcium out of my bones and I had terrible bone pain that kept me awake at night, and all they really did was mask some of the pain, and since taking them I now have OA in my knees which I didn't have before I took them.  If I could turn the clock back I would not have taken them.

PHPT is also often mistaken for fibromyalgia as well as PMR so be sure to get the right diagnosis, high calcium and high PTH (although there are a small number of cases where it can be high normal and still mean you have a tumour).

One final thing otherwise this will be too long - although it does cost (about £6,000 ish) for the operation in Tampa, over here if you have it done privately it is about the same cost and it is NOT the same operation.  In Tampa there is no large cut, no exploration of your neck and no long hours spent on an operating table and there is a faster recovery after a short anaesthetic with no damage to the vocal cords (I know of someone whose vocal cord was damaged and they have to have ongoing treatment for it).

I hope that the skills and expertise in the Clinic in Tampa will one day be practised over here but unfortunately by the time that happens a lot of people will be very, very sick.   I can only tell you my experience and that I am now cured.  The damage to the body is caused not by how high the calcium actually is but how long you have had the disease.

Also it's not advisable to get venous sampling - the surgeons in Tampa say this is dangerous and it is of no help with the diagnosis.  Also the intraoperative testing of the PTH is of no value - this used to be done at one stage but it is now known that this is not helpful (and it takes about 45 mins while you are on the operating table).

The gamma probe used in the Tampa Clinic is linked to a computer which measures in real time EXACTLY how much PTH is being produced by all the parathyroid glands so the tumour is removed and the levels of the normal ones left behind can be verified.

All this info is very important to the health of the people suffering out there so I hope it won't be moderated to the point where it isn't shown.  The bottom line is you CANNOT live with a parathyroid tumour, it slowly destroys your whole body and makes you very sick.  At the end of the day you need an acurate diagnosis and first class and prompt treatment so you can start to heal.  I know it is quite expensive, but it will ultimately give you back your quality of life and save your life.

Regarding symptoms, I had daily headaches, nausea, it felt like my brain was frying like an egg, I used to fall asleep by midday (a classic symptom), at night I had 'brain zaps' - just as I was falling asleep it was like having a crisp bag popped right in my ear which woke me up) and I developed heart palpitations and tachycardia (fast heartrate) and ended up in A&E because my potassium level dropped to a crisis level).  Since my op, my headaches have gone, my bones have improved a lot and my blood levels are much better (one of the symptoms is high liver results and mine were high).  High blood pressure is another symptom and I also had a pain in my left nipple which has also gone since the surgery.  

Again sorry this is so long but I hope it helps - 3 weeks after my diagnosis from Tampa I had my op and started feeling better (and took the opportunity to have a 2-week holiday in Florida before coming home).

Oh just remembered - the other thing about the gamma probe and computer - by knowing exactly how much PTH the tumour was producing, they can work out how much calcium to give you after the op and for how long and also there are different types of calcium and the one they prescribe is calcium citrate which the body can easily absorb.

I just wish the best for all of you out there suffering, I know how terrible it is, I just hope this info helps.

tampapatient

 

You sound like a "real expert" in this disease!  Almost too good to be true.  Why did you search out a forum like this now, after the fact??  

Also so you are lucky to go to Tampa in US for surgery.  Most of us cannot afford that.  Count yourself lucky. 

Oh my God this is my mum she's been suffering for about 10 years with no diagnosis they are now sending her to see a specialist as they think fibromialga and her gp keeps saying it's depression.

Her symptoms are the same as yours she also chokes all the time especially when lying down and going to sleep, pains in all her joints and high liver function tests for years which they have just dismissed.

Its only when I became I'll this year with similar symptoms I started to search for information and after getting a second opinion as I was told I had depression and a virus and I've never suffered with depression and I was to I'll to be a virus.

I also had a lump in my neck which is the only reason they refered me to discover I had a thyroid nodule which apparently don't cause symptoms and because my thyroid function came back OK they wanted to leave and monitor it the fnb came back benign.

Ibwas lucky as my surgeon believed what I was saying about how it was making me feel and decided to remove it I have quiet a big scar and my vocal cords have been affected but I can't tell you how much better I feel and I'm only 2 weeks post opp .

I just really want a diagnosis for my poor mum any ideas what she needs to say to the specialist seeing him on the 22nd of July xx

Thanks for your story and so typical of how patients are treated here in the U.K.  We do have a handful of decent parathyroid surgeons in this country but I think only one or two use intra operative measuring during the op to ascertain whether there is a second or even third adenoma.  As you say Tampa is state of the art and considering the charges for private surgery in the U.K. the NPC is very reasonable.  We have a private group on Facebook  Hyperparathyroid UK Action4Change with an excess of 700 members and are fortunate that we have one of the surgeons from Tampa on our group who is most helpful and did a long questions and answers for our members one evening last month.  If you would care to share your story there, please do.  The group requires a proper name (not an alias and in any case Facebook is now clamping down on obvious made up names) and say Elaine sent you.  Glad you are cured.  Regards Elaine

Cost at Tampa US$11,900, which is about £8300 for everything and there is air fare and hotel accommodation on top.

John Radcliffe hospital  (forgotten the name of surgeon)  £6000.

Mr Lynn, Harley Street £12 500, Mr Scott Coombes Cardiff around £5,500, same for Professor Wishart, Mr Jani and Mr Fish Cambridge, Justin Morgan, Gloucester, Mr Palazzo Hammersmith £8,000.  All the U.K. prices do not include scans and blood tests.

Hello Mommy7379

I am not claiming to be an expert, I lived with primaryy hyperparathyroidism for more than 6 years and got very ill and my story is true and is what happened to me personally.   I have told my story on another website and I am aware of Sallie Powell who is trying to educate people in this country about this disease which very few people truly know anything about - well done to her for being so proactive, I have read her story and know she suffered a lot with this disease.

Our NHS is in a real mess and under a lot of pressure and the wrong diagnosis happens a lot.  I had hoped that consultants here would be more enlightened by now - I spent a long time talking to an Endocrinologist on the 'phone at the request of my doctor before going to Tampa.

Yes it is expensive to go to Tampa but the experts there say the disease takes 5-6 years off your life and they rarely see anyone who has had it for more than 20 years or so because by then patients have died.  My problems were so severe I couldn't even get out of bed at one point and I could not have lived my life any longer like that it was just too excruciatingly painful to move.  Having it so long has caused me some heart problems but at least now I am cured they should not get any worse.

The Tampa clinic say that they can help people who would find it hard to pay for their treatment so perhaps that would be worth looking into.

They do a lot of re-op operations there from previous failed surgeries and anyone who has had a failed surgery would be wise to go to Tampa if they can because scar tissue from a first failed operation makes it difficult to carry out another and can resemble cancer under the microscope.

My tumour was not where it should have been and was difficult to find.  If I had not gone to Tampa, I would have needed a further operation to find it.

Whatever your personal situation, I do hope that you can find an experienced and good surgeon and get treatment that will cure you and wish you well.

By the way, I have only been to the States once for the sole purpose of the op but tried to turn it into something positive by taking a holiday there and giving myself time to recover before flying back.  It was a once in a lifetime trip, I won't be doing it again.

 

Hello elainec33 

Many thanks for your reply and all the info.  I am aware that we seem to have a few surgeons here in the UK who are better experienced with PHPT - but I don't think any of them has the gamma probe.

 

In my case I was one of the 20% whose tumour was not where it is normally would be and without the gamma probe it really is very difficult to find those ectopic tumours.  Dr Norman (who did my op) said mine was deep under my collar bone buried in my thumus gland so I made the right decision for me to go to Tampa where they have the probe that helps to locate the tumour.  

I just simply wanted to share my story and information in the hope that it helps somebody.

I hope everyone here finds a good surgeon and has a good outcome, most of the people on here (about 80%) will have their tumours in the normal place behind the thyroid, which is easier to find.  I unfortunately did not.

I am glad that you have a surgeon from Tampa giving you advice, I think that is Dr Boone who hadn't joined Dr Norman's Centre when I went there.  Dr Norman and Dr Politz did my operation and I was very well looked after.  Without repeating myself, if you look at my reply to Mommy7389, I have added a bit more info.

I wish everyone on here well.

Rosemary25383

I agree Tampa USA is best place in the world to go. I just cannot afford it.

Glad you got sorted, would be nice to spend some time on holiday after the op, a couple of friends have done that.  Forgot to mention before, that Sheffield has a gamma probe.

Elaine

Hello Elaine

Thank you, yes the Vitamin D top up on the holiday was a great start to recovery and improving my calcium levels (although you have to keep your scar covered in the sun for the first year).  I was the only sunbather on the beach wearing a scarf!!

Thanks also for the info re the gamma probe in Sheffield, that's useful to know.  That's a good sign that at least one surgeon has now got one. 

If you haven't had your op yet I wish you all the very best for that and hope that you will be cured of this debilitating disease.  For 2 years I was so ill (extreme joint and muscle pain) that I could barely climb stairs, get out of bed or stand from sitting.  Dr Norman said it could take a good couple of years to really feel better and he was right, the progress happens gradually but my calcium has always been in the normal range since my op and I feel nearly back to normal now.  I think when you''ve had it a long time and you are also not that young any more (yikes), it does take longer but the healing starts right after the cure and it does get better.

Another poster asked why am I on the forum since I am cured.  Well, discovering the tumour came as a big shock and it's one thing to get physically better but it does also leave a bit of an emotional scar and talking to other people who have it and sharing info that may help them helps.  I also hope to find that the medical profession are becoming more aware of this disease and that people are getting the right diagnosis.  We live in hope.

With kind regards.

Rosemary

 

Thanks Rosemary, I'm stuck between a rock and a hard place at the moment.  Totally useless gp surgery who were trying to get me to chew on 3000mg of calcium a day because I have advanced osteoporosis. I get all my results printed off as I dont trust anyone, anyway only to find that my calcium was over normal and she hadnt noticed.  So I decided to go down the private route to a good endocrinologist, wrong, again useless and even worse secretarial service who never kept contact, pth put in wrong bottle, ntx bone marker lost twice, etc. etc. one ultrasound with sighting of possible small adenoma, negative sestamibi.  Got really sick, all sorts going on, then my dad died, put on anti depressants because of the nausea that went on for many weeks, but wasnt depressed, all that did was make me depressed and agitated and put weight back on but all on the stomach, so am weaning myself off them.  Then went to top surgeon in London, his ultrasound man said different and feels there is an overactive thyroid and not really convinced of adenoma, ct scan didnt reveal anything much either.  More blood tests, then was told he didnt want to go poking around and not find anything, so being old school has put me on 50,000 IU of vitamin per week (my vitamin D was okay in March I sent away to the birmingham nhs assay people which only costs £28 and opposed to £105 for vit D done at the Spire, it was around 89 so not deplete.  He is hoping the doses of vitamin d will stir something up with pth and calcium.  Couldnt cope with 50,000 IU so got it up to 35,000 IU, had even worse bone pain initially but I have since read that mirtazapine can cause all sorts of aches and pains as well as the usual horrible side effects.  Am due to go back mid July, would have been mid June (the 12 weeks) but gp surgery messed about with prescription and apparently sent a message to surgeon that 50,000 capsules not available and did he mean 5,000IU (I bet that went down well) so I bought my own 5,000IU and the delay was around 4 weeks.   So to date, this experimenting with the private sector has cost me £5000!!   As you say, we live in hope.

Regards

Elaine

Sorry, now it's saying comment waiting to be moderated and I didnt put in any links and kept names in lower case!!  So why I dont know.  Like an idiot I didnt copy and paste to send it as a pm to you.

Maybe the robot didnt like me saying how "useful" the gp surgery and endocrinologist has been so far, lol.

Rosemary  I am 4 months post op for HH repair and Nissen Fundoplication  while recovering i told dr that i have been having palpitations and its scary....They thought it is spasm in chest due to Hiatal Hernia repair.I had heart monitor for 24 hrs nothing appeared of course..so its dismissed.   I went to primary dr who did blood work my calciun level is 11 which is High he said...Now went to chief of endocrinology and she did ultrasound she said the thryroid gland has a growth in it which is benign...she did needle biopsy 3 yrs ago and assured me its ok...bone density was done and i have osteo pinea ...August she will do recheck of blood work ...said i do not have to come back for 3 years.....i am not comfortable with all this as i again am having occasional heart flutter or palpitations whatever it be its there and dont like that feeling.  my primary said because the biopsy was ok we will watch and go back in 3 years.   I am still recovering from the surgery and dont know what to do but I dont feel great, all the gerd issues are gone thankfully..  But my memory is not as sharp as it was, and fatigue is here, but again is it due to recovering ...ii just want to be me again....any advice/  i did read about Tampa and it all sounds good....there is a $2000.00 consult fee i dont know if i should wait it out or what   ...tell me what u think pls   liz

Sorry you are suffering like this.  I dont understand why she did a needle biopsy, I wonder if she does?????  An adenoma on one of the parathryoids I would have thought indicated an operation.  Or did she say it was a nodule.  You didnt say, assuming you had a pth test done, what that was.  It is all very difficult, I thought I had found a good private endocrinologist in London but I was wrong.  Is there any way, you could find a decent endocrine surgeon in your area and make an appointment directly.  I am on a private group on Facebook  Hyperparathyroid UK Action4Change and it seems that going to a surgeon direct is the most popular move because of the endocrinologists' lack of knowledge about parathryoidism.  I dont know what 11 is as that is the U.S. measurement for calcium.  If you want to join us, you would be most welcome and might find out a bit more information.  Just say Elaine sent you.

I just found this on the Tampa website

To convert mg/dl to mmol/L: Multiply by 0.2495.  To convert mmol/L to mg/dl:  Divide by 0.2495. Thus a calcium 10.0 mg/dl = 2.495 mmol/L.  A calcium of 11.0 mg/dl = 2.75 mmol/L

English version

Normal calcium readings are:

2.1 mmol per litre to 2.6 mmol per litre.

So yes your calcium is high.  when it reaches 3.0 is very serious

Normal pth readings;

normal range 1.48 to 7.63 or 1.6 - 6.9 in the UK, (for some reason the readings vary in the U.K.

and around 15 - 65 in the US,

Hello Elaine

That's bizzare that your message hasn't come through - maybe the robot just doesn't like cats and damning with faint praise - fussy isn't it!  lol

(I love cats by the way)!

 

Hello Liz - I have been out all day and not long back and have just seen your message.   Poor you!  I am so sorry you have been through all that and that you feel so poorly.

The one thing that is not very clear from your message is whether the growth is on your thyroid gland or whether it is an enlarged parathyroid gland,  I'm guessing that you are quite young.  Thyroid nodules are more common in people as they get older and many people get them (says Dr Norman) and they are usually harmless,

However, the symptoms you describe sound suspiciously to me like the symptoms of parathyroid disease.  I am not a doctor but I had those symptoms.  Before my PHPT (parathyroid) symptoms increased, I used to get nausea and would vomit after eating things and there was no obvious reason why that was (in retrospect, that must have been the start of my high calcium levels because that's what it can do) and quite a lot of people get GERD with PHPT.

I also had a fluttering feeling in my heart and the awful palpitations you describe and visited the doctors as a result who just said that there was no obvious problem (and implied it was my age!!  It is, however, a symptom of PHPT.  Your calcium level is high being 11 and if you get a PTH blood test done (parathyroid hormone) and it is high as well, the 2 high readings together mean it is very likely you have a parathyroid adenoma.

Also you say you have osteopenia (thin bones) - well, that is a very common symptom of parathyroid disease.  If the calcium level in your blood is high and you have a high PTH too, the calcium is being leeched from your bones by the high PTH level and the bones are getting thinner and weaker as a result.  Parathyroid glands regulate the calcium levels in the blood within a tight range (bit like the workings of a car), and when there is a tumour the level of PTH spirals out of control.

Parathyroid disease wreaks havoc with your memory and concentration because the central nervous system incuding the brain is affected by the levels of calcium, it needs just the right amount to work properly, not too much and not too little.  

If I was in your shoes, I would get your PTH checked first of all and if it is also high, then there is definitely a problem although in a minority of cases a high normal result can still mean there is a problem.

To me you sound like you may be in your 20s or 30s, I may be wrong, but if you do have a parathyroid adenoma, not having it removed means your bones will continue to lose calcium and eventually it will lead to osteoporosis.  If your doctor isn't very helpful, then it would be wise to change him/her and get a second opinion.

Dr Norman in Tampa says that when doctors don't know what to do, they do NOTHING and waiting another 3 years - what !! - when you already know you have high calcium is going to make things worse.

I know that Dr Norman's clinic does charge quite a lot of money to have your results analysed (I didn't have to go there to do that, they can do it by email/post if you send through your results) but they are a truly specialised centre and Dr Norman really knows what he is doing.  I have heard that if when you send your results to him and he checks them and finds that you likely don't have a parathyroid tumour, then I think the bill is less (unless things have changed recently).  You need to send a series of calcium levels and PTH blood test results and a copy of your bone scan etc and it takes them about a week to prepare a personal chart for you.

......I will send you this then continue in case the text gets lost, back in a minute............

 

.......Some people think the consultation is expensive for Tampa but there is quite a lot of work involved in analysing people's results and creating a personal chart for every patient.  They also write to your doctor after surgery with all the info and pathology report and also send a colour life-size photo of the tumour(s) they remove to you and your doctor.

The other good thing is that although the Tampa surgeons do not carry out thyroid surgery per se, if when they have a parathyroid patient they discover a problem with the patient's thyroid, then they fix it at the same same time and I think that is very good.   So, if you are able to pay to have all your results analysed, it really is worth it (and I do feel for those people who cannot).

As you have already had surgical interventions, if it did transpire that you have a parathyroid adenoma, then if I were you I would go to somewhere experienced like the Tampa Clinic because you don't want to have a failed operation.  As I said in an earlier post, they have state-of-the-art technology and many, many years of expertise.  Also the operation is done under a local anaesthetic in usually less than 20 minutes with just a 1" scar and a quick recovery.  You normally leave the hospital in 1-2 hours later so there is no overnight stay (it would be extremely rare).

I can speak from experience that the whole experience there is exactly as they say it is on their website, it is all true.  

I think from your message you may be in one of the American States?  You may even be in Florida, NPC has a lot of patients from there - and very telling is the fact that a lot of doctors with parathyroid disease go there!

I hope the above info helps you in some way.  It would be nice to know how you get on and what road you decide to take towards getting better.

The very first step is of course to check your PTH to see if you do have a high chance of having a parathyroid tumour.  If not then your problems are due to something else but it's worth checking everything out and ruling out the parathyroid problem first.

I hope you feel better soon from your current surgery.

Kind regards.

Rosemary

p.s. my surgery at Tampa was so non-invasive that when I had my op, I only lost about 3ml of blood (that's about half a teaspoonful)!!