Metformin

Just had my annual  type 2 diabetes check up and the Doc has changed my Metformin medication to Alogliptin / Metformin combination tablet. He says it is a new drug with good results reported. Anybody else have any experience of this ?

 

Hi James 04405

I have not heard of Alogliptin, but wonder if it is related to Sitagliptin as I am on that one as well as Metformin. I have been on this combination for some time, because if I just took the Metformin, I would have to take up to 3000mg and my doctor said to much is not good. That would also relate to the slow release type as well.

Sitagliptin / Metformin is the combination that he has moved me from. My results are good and there were no isuues with my annual check up but he wants me to try this new combination and re-test in December. I don't have an issue with the change because I do actually have confidence in my GP.

 

Hi James 04405.

I have been on metformin for 10 years,six months ago my sugar level was creeping up, so when i went for my check up,the GP said i should start taking Sitagliptin, one a day,i took them for 2 weeks ,they did not make any difference ,so i thought mybe one a day is not strong enough,so i took 2 a day, 1 in the morning and 1 in the evening, low and behold my sugar level dropped away down,to where it should be,now i go and see my diabetic nurse,and she told me my levels were in exellent shape,but when i told her what i had done ,she flipped,and said i should not do that, as it could cause me to have bleeding ulsers in my stomach,needless to say i had to back off the 2 a day,but i really have to keep a check on my sugar levels and i have got to stay away from eating any kind of chocolate biscuits or bars or ice cream,and my problem is i have a sweet tooth,and had it all my life,all im saying is, just keep an eye open since your taken them ,and the reason i say that is my diabetic nurse was all for taking me off them all together, i go back to see her on the 13th Aug,i am just wondering what she will say this time .

Hi jim48819

I only take 1 Sitagliptin a day with my Metformin, yet I don't eat any sweet products unless I need to. The only thing is that I can't recall as to when I had my last diabetic bloods & health check, I know for a fact that I don't check my own sugars.

Does Metformin give you any problems?

I take Metformin1G/Sitaglip50MG without any problems twice a day at meal times.

I have a combined tablet Metformin 1g with Sitaglip 50mg twice a day without any issues. My local Heath authority don't want me to check my own sugars but call me in once a year to a Diabetic clinic and give me a once over. I had a problem with Ramapril and they swapped that for a Losartin and my problems cleared up within days.

Metformin gave me ulcer like stomach pains about two hours after taking it.

It made no difference if I took it in the morning or in the evening

Hi, no not really, but sometime i get the idea i have  taken them so long, that they are not doing me any good, and the reason i say that is, over a period of time ,and the fact i have more health problems, i am now taking 91 pills a week,which gives me a lot of thirst problems and lots of constipation problems,and every time i go to my GP they just seem to give me more pills,it gets very confusing at times.

Hi Mark,

how long have you been taking Sitagliptin.

My combination of medication taken twice a day is as follows;

sitagliptin 100mg

Metformin 1000mg

I have been talking Sitagliptin for just over a year.

I take it as follows;

sitagliptin 100mg twice a day.

metformin 1000mg twice a day.

Most of the people I know are the very opposite of constipated when taking Metformin.

My neighbour was on a vast amount of pills until she changed doctors.

I could not help but notice you reply to jim and with all of the tables I take per week (161) I am the opposite to the constipation as I can get into difficulties if food is not cooked thoroughly. But I take Loperamide 2mg twice a day and mainly because that one of the ingredients my system disagrees with.

161! That should be a record but no doubt someone will better it. Have you ever worked out the annual cost of them? 

Hi Mark, i take metformin 850mg twice a day and have for 10 years

i take Sitagliptin 100mg once a day, and have for the last three months.but like i said previously the Diabetic nurse does not want me to take 2 Sitagliptin a day,and when i asked her why not, as when i take 2 a day it seems to keep my sugar level down,her answer was, and she was looking in some book, when she was answering me saying thats what it calls for,i said to her but maybe when they put that on the market thats what they prescribed, but maybe that dose does not work for everyone,thats when she came back at me with, it can cause you to have stomach ulsers that can bleed,thats why i say it gets confusing,and also i may add i thought i was taking a lot of pills 91 a week ,and you say your taking 161,,the pharmsutical companys must be making a fortune.

Hi jim48819

I already have stomach ulcers, which I have had for many years and I am taking Omeprazole 20mg and Ranitidine 150mg both are daily. So I take them at opposite ends of the day.

I dread to think. But I am on permanent sick due to CMT (Charcot Marie Tooth Disease) this you will find on the internet if you want as it would take to long to explain.

I am also in remission for bladder cancer. Had a mild heart attack, Both knees replaced and all toe joins fused.

Now I am having to deal with an enlarged prostate.

Apart from that I am in good spirits.

Hi Mark,

You have a good attiude,and im sure it will help you,especially with the condition of your health,and between both of us, we seem to have our fair share,i myself three years ago went in to hospital for a small simple operation on my eyes,from there everything went wrong,and from someone who never took pills in there life,i am now as as i have already said am taking 91 a week,after my operation, they were suppose to keep me in for the day,and if everything was ok i was to be released the next day,i think  they needed the bed, so i was released the same day as they said i was fine and i could go home,but funnily enough 3 hours after i was released,i was doubled up on the floor in my house with pain as i could not urinate,even though i had a real sensation to empty my bladder,i was back in the hospital immediatly after calling them,now even after going back they checked my bladder with one of these scanners,and said what we think is your system has kicked out as you had a general annaseticand it will probably kick back in with in a couple days,as it often happens,so you stay here to night and have an uncomfotable night, or you can go home and have an uncomfertable night,so it was almost 10 o clock, so i said, ah well if its only for a couple of days i think i can handle that, i will go home,big mistake,as i had to go to my GP 3 days later, as i was still having problems trying to empty my bladder,he gave me some strong pain killers,end result was i went 10 days could not empty my bladder, with out difficulty, i could not eat, i could not emty my bowels, and in that 10 days i lost close to 2 stone in weight,after i was rushed to hospital in an emergency right from my GP office, as i was just about ready to collapse,they finnaly in serted a catheter,in to me and i released one and a half litre of urine,my bladder had be stretched for 10 days ,my kidneys was not functioning properly and i lost 2 stone,they kept me in for a couple of days and had to put me on a drip as my water levels were a way low,they had me caterize my self for 6 weeks,after they took the bag off and asked to urinate i could not do it ,thats when my trouble started,they said the fact that i cant urinate we will have to go in and see what is going on,so they checked my prostate,and said your protate is enlarged, so we will have to take a biopsy which they did,they found cancer cells,and i had to go for 1 month of radiothearphy everyday for a month, and they said i should go fo some hormone treatmentwhich i did and have done once every 3 months for the last 3 years i go for a needle in my stomach,and i finnished up with nearve damage ,which i believe was through the lazer treatment i got when i was getting the radiothearphy,the only advice i could give you Mark is,if you are not haveing any problems with your water works,and before you let them take biopsies,make sure you know what you are doing ,and the reason i say this if you give them permissinn to take a biopsie there is a very good chance with your age they will fined cancer cells,but just remember this Mark even if they do find cancer cells ,they cant tell if they are fast growing cells or slow growing cells and if they are slow growing cells they can take decades to flare up,so in other words if you give them the ok to do the biopsie, and they come back and tell you they have found some cancer cells,then you dont have a choice ,if i knew what i know now Mark ,i would have went on the wait and watch program,that way if your not haveing prob;ems with your water works,you dont have to take a chance of getting all these horrendous side effect,on the wait and watch the DR CHECKS YOUR psa, you go back in 3 months he checks it again, and if it has not went up, he will see you again in 3 months or 6 months whatever,there is guys doing that, its worth looking into Mark,because the side effects i got were horrendous thats why i am on morphine every day .