Has anyone been taking prednisolone and changed to prednisone? If so, what was the regimen to make the change? Also, was there a noticeable difference in direct effects or side effects?
I just took prednisolone one day and prednisone the next.
Thanks, ptolemy. When you transitioned what was your dosage of Prednisolone? Did you notice any difference?
I think it was around 12.5mg
And noticed no difference in your stiffness or pain between prednisolone and prednisone?
I found reduction easier, but the tablets were quite new ones with special coating.
Why are you having to change? Prednisone gets converted to prednisolone by the liver.
Do we know why some people are prescribed Prednisolone rather than Prednisone? I know the difference is connected with what the liver does but wonder how the decision is made in the first pls e.
My medrol (methylprednisolone) is not available in 1mg tablets and prednisone is. So slow reductions are more difficult with medrol.
Do you mind telling me what your current dosage of prednisone is? My medrol is 8mg - equivalent to 10mg prednisone.
Fair enough! I am on 7mg reducing to 6mg.
I'm on Prednisolone, currently 10mgs.
I do not know the answer. My primary physician started me with medrol but a rheumatologist wants me to change. His only reason seems to be the availability of 1mg tablets for prednisone.
sorry, I now realise you were asking Ptolemy, not me.
And your general condition is good?
Not a problem. For information, if anyone is interested, I'm active with some stiffness but hardly any pain unless I really do heavy lifting or such.
It does seem to be related to where you live to a certain extent. UK offer prednisolone and the US prednisone in general for PMR. Maybe it is also related to price negotiation with the different drug companies.
I'm in US, so medrol was apparently an unusual choice.
I have had a lot of side effects from the steroids, they did seem to reduce when I swapped though, but that may have been due to reduction. I had taken virtually no drugs throughout my life before pred, I had never even had paracetamol or an anti biotic. I wonder if that is why I had so many side effects.
That's interesting. All I know is that the liver doesn't have to convert anything with the Prednisolone. The job's been done.
That is what my brother said, prednisolone saves my liver, so I can have an extra glass of wine! Perhaps I should not have changed!!