Rote juckende Beulen

My husband has been getting these weird bumps hard knots red burning itchy under his skin his ankles his cafe elbows thigh seems like they appear in different places and the crazy thing he wakes with them they don't seem to come during the day he notice them in the morning after waking I don't have a clue

I would call his PCP or Dermatologist. It definitely does not sound like an STD.

It's just weird he sleeps then by morning he notices these red area that gets very hard on his ankle then his cafe now his arm and thigh we checked for possible bed bugs but no signs of that also they are very hard knots that itch like crazy

I checked Google. It sounds like bed bugs or maybe mites. Do you have pets? A rabbit maybe? We got mites once in my house. I would go ahead and strip you bedding and wash it in hot water with a mild, dye free detergent and spray the bed with mite/bed bug spray and let it dry.

It's weird I've never gotten bitten or anything else its just him that's getting them I have seen what bed bugs look like and the bits my sister had them but his lumps look nothing like what her and her children had

How about these pics?

http://www.healthline.com/health/bug-bites