Im on my third dose of taking methotrexate. Not noticed any change and side effects have been manageable BUT after an hour of taking it my lower back is agony. Its like im being stabbed all over. After 2 or so hrs it goes. No painkiller touches it.
Anyone else had similar reaction??
Many thanks
Gosh, please stop taking this medication until you do some research on this..this could be greatly effecting your kidneys.. Can you tell us why you are taking this daily? This normally is taken one day a week, starting with 2 or 3 tablets..
Hello.
Sorry I take it once a week for RA. This is my third week and each time my back hurts. Its in the muscle area that runs either side of your spine. Its horrible.
Gosh, please stop taking this medication until you do some research on this..this could be greatly effecting your kidneys.. This medication has strong warnings regarding risks with kidney failure leading to death..Can you tell us why you are taking this daily? This normally is taken one day a week, starting with 2 or 3 tablets..
Meant to say ive started on 6 2.5mg.
There is what's called referred pain..which sounds like is a possibility from where you've described your pain..would you say this is in your low to middle back? Have you asked your doctors nurse, or called a nurse in your local ER to get her thoughts about whether you should be seen right away? Methotrexate is associated with liver toxology and and serious co morbid complications. You may want to get a few professional opinions and your own feelings about this before taking another of these. These were poison for me and caused all over pain and cause a compromised immune system leading to infection in the body, including kidney infection, dental infections, ( loosening of teeth and infection getting into the roots and then becoming systemic, and other infections) ..
This drug makes me think i'll get worse not better. Its from middle to lower back. I have osteo in spine so it may be aggravating that. Ill call rheumy nurse tomorrow. Thanku. X x
I have been taking methratrexate for couple of months and nothing like that. I do drink two big glasses of water when I take it. I am up to 20 mg and all I've noticed is hair loss. I would call your Dr just to ease your mind.
Thanku I will. X
Hi Donna, I took MTX for 18 months until I could no longer tolerate the pain it caused in my hips and thighs. I stopped taking it in February and still have pain, though it is now tolerable.
Talk to your Consultant. I have now spoken to mine [Dermatologist] and he is looking to put me on a different drug
I took Co-Dydramol at night, which helped me sleep through the pain for a few hours but, as you say, nothing much helps.
Hello
Thanku I will speak with him. Its also making my neuropathy worse so something is not right.
When I mentioned the pain to my Dermatologist, I also remembered that I had had pain like that, when I took Alendronic Acid. He asked me whether I had taken Atorvastatin, which I had and I had also had to stop that because of leg pain. The Atorvastatin was about 15 years ago, so I don't know what he was thinking about. We are discussing it further in 3 weeks time.
Let me know what he says. I know mtx can cause neurpothy so im assuming its making mine worse.
Ive apoken with consultant and ive got to split my dose. Three on sunday then three on Wednesday. We will see what happens.
speak to your Dr or Rheumatoligist asap as it sounds like you cannot take that much medication in one go or that drug with out some sort of steroid pain killer
Hello
Ive spoken with my specialist and he has recommended splitting the dose. I took three last nite and will take three on Wednesday. It worked no pain.
Fingers crossed it carries on. :-)
I am wondering if you have stopped taking the methotrexate...? Side effects from this drug greatly lowers our immune system and induced pain in so many places in me....is toxic for many and symptoms like yours are listed in the medication insert guven by the pharmacist as toxic reactions to this medication.
hope it works for you
BTW do you take folic acid tablets to rebuild your damaged bones ? as you cant take them on the days you take Methatrexate
Thats such great news.. Do gou also take prescribed folic acid to prevent any nausia from the depletion of this from methotrexate?
Folic acid is depleted immediately when using methotrexate from the blood and causes extreme nausia if not taken. They are ti be taken on days when methotrexate is not taken, either 1 time wkly at 5 mg or 1 mg daily.
hi know as i have been taking folic acid tablets for years now i take so many differant tablets on the Methetrexate days i sound like a Spanish maracas still i dont care as it stops the pain and i still function and work
when i was diagnosed and prescribed Folic acid tablets i thought i know i had a big tummy but i am not pregnant as i thought thats its was for pregnant women but i was wrong its helped me no end and i have not had any side effects from any drugs i am on and i also tapered right down on some of the Methotrexate and also Prednisalone but started to get flare ups so the Methotrexate was increased to 20mg a week but still suffered until the Prednisalone was increased then the pain stopped so i will be decreasing the Methotrexate again and staying on a holding dose of Prednisalone