Redução gradual de Mirtazapina - Minha Experiência

Tratamento e medicação
1

Hi all,

This wll be a brief record of my experience coming off Mirtazapine.

Writing it down might help me stay focused on my goal and I'll try and answer any questions for others along the way.

I've been on 15mg of Mirtazapine for 15 months now.

For the first 9 months it worked wonders for me. Instantly helped with my sleep and anaxity. I can remember telling my doctor how amazed I was with it! 

After 9 months I started feeling I was getting more and tired in the days. 

It was effecting my focus, concentration and memory. I was groggy in the morning till 10am and dozy in the afternoons from 3pm. I was feeling a bit out of control. Zombie like.

I had a decision to either up my dose to 30mg, as higher doses has less of a sedation effect. Or to try and come off it.

I decided in the long run, increasing it would only make coming off it harder in the end so I would TRY reducing it.

I started cutting a tablet into quarters with a craft knife, and taking 3/4 or 11.25mg a night.

For the first 2 night it didn't sleep well but felt about the same in the days so pushed on and it passed.

I always do my drops on a Friday night so I have the weekend to ride out the worst of it.

After 2 weeks I dropped again to 1/2 a tablet or 7.5mg.

This was a lot harder. I was in a really heave sleep until 9am the following days, woke up with a banging headache and couldn't do much all day.

It has been like this for the first 3 days on 7.5mg.

I am tempted to go back up but seeing as I have done 3 days now I will keep pushing on.

I know it is going to be a tough few weeks but I am going to do positive things to keep on top of it.

The classics. Eating well. Exercise. Vitamins and Omega-3.

2

On a side note;

I have also found Mirtazapine has effected my skin. Making it feel more sweaty and sticky. Which has even lead to a few persistent skin rashes, which have not been effected by the standard creams. 

I've search online for any links between Mirtazapine and skin conditions but to no success.

As I've lowered my dose I can feel the stickiness slightly worse so I hope it clears.

3

Hi,

i also found that the medication caused a red rash on my face.

 

4

David,

Eu estava com uma dose de 45 mg e agora estou em 15 mg e tive dores de cabeça, olho seco e nervos à flor da pele ao redor dos olhos, então, para dizer o mínimo, tem sido um remédio horrível para eu parar. Já faz um pouco mais de um ano que estou tomando e funcionou bem para mim por um tempo também.

Me avise como as coisas vão, pois estou interessado em como você se sai. Boa sorte e espero que tudo dê certo para você!

5

Caro David

Eu gostaria de ter um registro de todas as pessoas que sofreram sintomas semelhantes aos seus (e aos meus). Sim, o Mirt pode parecer milagroso tendo sofrido de Ansiedade e Insônia (eu também), mas depois de algum tempo parece que nosso sistema se transforma em uma espécie de síndrome de fadiga crônica que é difícil de superar. É tão comum com o Mirt.

Não tenho certeza se você já leu antes que para reduzir o Mirt deve ser feito após alguma pesquisa para evitar sintomas de descontinuação/abstinência - que podem incluir insônia, náusea, ansiedade e até mesmo enganá-lo (uds) fazendo você pensar que temos sintomas antigos retornando (reação). Portanto, é sábio ter uma escolha informada e, em seguida, fazer um plano para reduzir o Miort - para ajudá-lo, você pode querer se informar - clique no meu nome e siga os links sob meu status. A regra de ouro parece ser não mais que 10% a cada 3-4 semanas, deixando tempo para seu SNC se recuperar a cada vez, e, se em dificuldade, esperar pela estabilização.

Vejo que você fez uma redução de 25% e agora outra redução de 33%, o que pode causar alguns WD extremos, porém você pode ser um dos poucos que podem tolerar a redução de doses nesse ritmo, bem, eu espero que esteja tudo bem para você.

Desejando-lhe o melhor e esperando uma saída segura e fácil do Mirt.

Melhores votos.

6

Rob - Interesting that you mention the problems with your eyes.

The last 6 days my eyes have been dry, even the skin around them. They are also a bit twitchy and sore.

It had been a busy week so I put it down to tirdness but sounds like it could well be the Mirtazapine.

Calmer - Thanks for the advice and information on tapering. My new doctor has been particularly unhelpful so I am doing it under my own research.

I am confident he would say I can come off it if I feel ready and that is what I personally want to do.

It seems lots of the medical advice is is to go from whole, to half, to quarter, to off, every two weeks.

However, personal accounts often say how hard this is to do and find the only we to do it is very small changes as you mention.

Unfortunatly I typically have quite strong reaction to changes in medication so I wouldn't be surprised if I needed to slow down my tapering. However, I was getting to a stage where the side effects were almost as bad as why I went onto it in the first place.

As with a lot of medical advice it is about trying it and see how you respond. 

7

 Olá David, Estou tomando Mirt há 8 semanas, 15mg. Aumentei para 30mg há cerca de 3-4 semanas. Comecei a notar uma erupção cutânea em ambos os lados do meu pescoço, onde a gola da minha camisa repousa, e às vezes coça. Tenho certeza de que isso tem a ver com o Mirt. Deus te abençoe, Bob

8

Oi David, há cerca de um ano fui receitado 15mg de Mirt, que tomei por cerca de 6 semanas. Comecei a me sentir melhor e reduzi para 7,5mg e essa é a dose que ainda estou tomando. Adoraria parar completamente e estou interessado em saber como você se sai se parar. Boa sorte e, por favor, me avise como foi.

9

Hi David!

I too have started to taper. In fact i started my taper 2 days ago. I was on 15 mg of mirtazapine and I am currently taking 3/4 tablet (11.25mg). I have heard of the 10% taper golden rule. But my physician and pharmacist have recommended 25% taper. Seeing as you too are doing it this way....I would love for us to keep a dialogue of how we are doing for support! I am two days in and I feel good. Also drinking plenty of water to flush out the medication, taking vitamins and staying positive.

10

Só queria saber como você está indo na sua jornada de redução? Eu passei de 45mg para 15mg desde maio, fiz a última redução há 4 semanas, então vou manter até depois do período de Natal e Ano Novo. Fiz a primeira redução de 45mg para 30mg seguindo o conselho do meu médico, e sofri todos os sintomas de abstinência, suores, tonturas, sensação de cabeça nadando, náuseas, diarreia, pressão arterial muito alta, tive que começar a tomar remédios para pressão arterial, sempre tive uma pressão arterial muito boa, picos de ansiedade, enxaquecas severas, foi um bom mês até eu fazer pesquisas e perceber que eram sintomas de abstinência, então fiquei nessa dose por 3 meses e eventualmente me senti muito bem.

Na próxima redução, passei para 7,5mg e sofri quase os mesmos sintomas, mas consegui superar. Desde então, venho reduzindo por um quarto de um comprimido de 15mg, e os sintomas de abstinência parecem ser os mesmos, mas acabam se estabilizando. Estou pensando em pedir para ter a medicação em líquido para fazer uma redução ainda mais lenta depois do Ano Novo, mas não tenho certeza se vou conseguir, pois é muito caro e o médico não reconhece a necessidade. Até liguei para o meu farmacêutico, que disse que nunca teve ninguém com problemas de abstinência! Acho que ele deveria ler este site.

11

Well, I shouldn't have a whole lot of problem to get off. I have been taking 15mm for the last 6 days and 7.5mm the 7th day. Today is the 8th. The fierst 3-4 days it was ok however; the 5th and 6th day I felt like a zombie. It took me 3-4 hours to concentrate and be able to remember and think. I 've tried other antidepressants, but I never remember these kind of side affects. Now my problem is should I take a half again tonight, or take a whole then follow two nights of halves. Any suggestion? I am a senior lady and it can be these meds interfere with my blood pressure pills. One thing I know mirtazapine is not for me. I still work in the morning and I need a clear mind to drive.

12

Estou tentando reduzir a dose de 30mg porque minha visão está ficando cada vez pior. Qualquer conselho será bem-vindo.

13

Mirtazapine is horrible. I started it for anxiety and insomnia. All it seemed to do was make tired 24/7.... The worst fatigue ever, have intense hunger and make me angry and aggressive. I have no idea why this drug is pushed so much. So many people have had bad experiences with it and it can also be extremely addictive. Awful drug.

14

David Sorry about your trouble with the Mirtazapine. I too started on 15mm but after 2 weeks that I couldn't weak up in the morning I tapered it off to 7.5mm. So far I am still taking the 7.5 but I'm gaining weight and still have hard time to weak up. I will be seeing my Dr tomorrow, but I am not intending to stay on this drug. Mirtazapine is not a drug to stay on for long time.

15

Hello pam, how is it with you? have you managed to get rid of mirt? I have the same problem with you. currently I am in my third day of tapering off from 15mg.

16

Well,now I’m concerned about weaning off mirtazapine… I’ve been on 30mg for 5 years for mental health reasons.. I was hoping to be able to get off them, but after reading peoples comments I’m not so sure now..

17

hi everyone, ive been on mirtazapine for a year and a half! i was 15mg but a month ago i cut down to 7.5mg. i felt really strange at the start, anxious and irritable, the main reason i used them was for sleeping/ anxiety. so after about a week and a half on 7.5mg i decided to have a drink to handle the withdrawal symptoms which really worked but i found myself drinking a lot more than usual! now im afraid to stop excessive drinking because of more withdrawals because i plan to get rid of this poison from my body. the biggest regret for me was taking mirtazapine in the first place! has anybody else tried alcohol to ease the withdrawal symptoms?

18

Thanks for your feed back Adrian. I’ve been on it for 5yrs 30mg.. Have been weaning myself off now for the last 5 weeks have just about got off them with near zero withdrawals. so i guess some have problems and others others dont. Also depends on strength of mind..