Venlafaxine - dosage of beads within prolonged release capsules

Hello...i need to taper down really slowly...over years i suspect...from venlafaxine as i've had no success with more conventional/faster methods. My plan was to remove one little bead, see how it goes for a week, then two etc...However, they're all different sizes! Does anyone know if the size is related to the dosage of drug or to the amount of coating (i.e. the the bigger beads relase their drug later than the smaller ones)?

Thanks

This is what I just read on a reduction website...

"If you have been opening the capsule and trying to sort and count the balls to reduce the Effexor XR please take special note. The people that have tried this approach seem to do ok until the second or third reduction and thereafter have a very difficult time with withdrawal. Knowing which balls contain what is impossible. We strongly urge you to avoid this approach"

Best approaches suggest reducing by skipping one capsule every 3 days ie:

If you are currently taking 3 x 75mg daily, you would reduce to just two capsules every third day so it would look like this:

Day1: 3 capsules

Day2: 3 capsules

Day3: 2 capsules

Day4: 3 capsules

Day5: 3 capsules

Day6: 2 capsules

And so on...

I was going to do this but you have no idea as to which is which inside of capsule. That is why I went to a pill of less mg.  You could be taking out the wrong ones or maybe too much of one thing or another.

Leanne

Hi lucy159,

I was on Effexor I am in Us. Not sure if the doses or time release caps are different . My husband has been a big help to me. I  got up to 150 mg over a period of 13 years. Sick of being 35 lbs over weight and pretty much a slug with help from my husband I slooowly have been decreasing the dose . My husband tried to take a 10th out at a time if you have capsules . He eye balled the amount and decreased 10 caps at what he judged to be 10% at a time . We decrease every 10 days. It is not easy but you have to hold it to the light to make sure the caps are equal. It's been about 2 1/2 months and I have about 13 days left to go. I still have crying spells , but don't have severe brain zaps that most have . I repeat I still have withdrawals. I have read blogs of people who have decreased by 1/3 each time and let me tell you . As hellish as it's been I would do it this way if I had to again. Coupled with counseling and my husband reassuring me it the withdrawal symptoms it's not me I'm not crazy and that I'm not going to stay like this it's going well . I wish you the best and hope you can find or have someone to help you get through this I t will be worth it in the long run. Try it it's well worth it hit. Just when I think I'm in the clear I get the side effects of getting off the drug but keep going.  Hope this has helped I'm on my phone and typing on my phone isn't easy for me good luck!! We can all conquer this!! And take it from there!

Thanks so much for all your comments, it's given me a lot to think about!!

Last year I tapered down very slowly from 150mg daily and had no withdrawal symptoms at all.  In UK capsules go down to 37.5mg dosage and because of this I went onto the generic Venlafaxine as they are poills.  I then bought a pill cutter on line and cut the pills into smaller and smaller amounts.  I don't think the method of taking out the beads is easy as, like you say, you do not know how this affects the withdrawal.  I do recommend my method as it really worked well.

I know it took me a long time, and you may wish to do it quicker.  I found with the pill cutting I could regulate how fast I went, and I did it really slowly just cutting off a little at a time, until in the end I was taking a tiny amount on my finger tip.  Your doctor will be able to prescribe the Venlafaxine pills.  My doctor got me so far with reducing from 150mg capsules to 37.5mg capsules,but was not sure how to proceed after that, so I decided for myself, and the doctor prescribed the generic.

I know this method does work, and I wsas on Effexor for 9 years and I am 73 years of age, so I believe if I managed to withdraw without any side effects, it can be achieved.  I am not a strong person, but I was determined.  It is a year now since I stopped, and so far no depression, but I admit anxiety has come back, but not too bad.

I hope this helps.

I went onto generic pills too, and cut them into smaller and smaller doses, and this worked very well for me.  It took me 10 months to withdraw from 150mg capsules, but I had no side effects, and that was a year ago.  Have you withdrawn yourself?

Hello I withdrew over 10 months by cutting generic pills to smaller and smaller doses, and had no withdrawal symptoms.  It is a year now and I have lost all the weight I put on whilst taking Effexor.  I had no withdrawals at all by taking it really slowly.  It can be done.  

Hi,

I was taking 37 mg for about 3 years and then 75 for a few years and then 150 for a couple years. I wanted to go off and tried cold turkey and found myself so sick. Then I went to 75 mg for 2 weeks and then every other day for 2 weeks.  Once again I was sick and now am going on 37 again for 2 weeks and then every other day for 2 weeks. I cant beleive this drug is so addictive to our system that it causes this much trouble. Hopefully now this will work and I can finally be off for good. As I have stated before mine was for hot flashes over the years day and night and not anxiety, where I was luckier than so many.

It wasn't easy taking out the time released balls but I had just gotten a 90 day prescription filled. 😁 My husband did the reducing and wasn't so hard for him do. 

Just suggestions you need to do what's best for you for you . Best of luck!! 

Thank god for my husband he was a great help! I don't think I could have doe it with out him . I have about 10 days to go and I'm done. Hear it takes a couple of weeks after that . To feel "normal" whatever that is ..again. I just hope the weight loss follows !! 

Maybe I should ask my dr for the 37.5 mg tabs when I see her nex week. Cut them accordingly. We thought the time released balls were all the same they look that way.  Still have   minor side effect still enough to prevent me from doing things I would normally do.    

Thanks everyone! Thank god for these blogs!

The 37 mg come in a tablet and not the time released like the 75 and 15 mg.  I just started on them today and hope this works out for me. Good luck to you

I meant 150 mg and not the 15

Hi,

I got so sick that it was terrible as I was naucious, light headed, just couldn't function at all. Hard to beleive a little pill can effect you so much. I beleive it does take a few months to come off it all together by doing it very gradual.

Keep trying you can do it . These pills mess with our minds . Maybe reduce in smaller  doses. Do you have pills or capsules . Sounds like the pills are easier to cut . My dr also gave me Xanax. I didn't want to get hooked on those so I woul take a 1/2 or 1/4 when things got bad. Hang in there I'm not done yet but it does get better. Think of how great we are going to feel when we are off this crap!! I'm looking forward to the weight loss. Keep up the good work!!

I too am waiting and looking forward to the weight loss. I have about 30 extra LB and I always diet and exercise and while on these pills nothing works.  Good luck to all of us.

Thank you so much Anne, this is really helpful...and gives me a lot of hope!! It sounds like you're a very strong person by the way...this is the first post i've ever come accross where someone has said they experienced no side effects!! x

I work out 5 days a week and eat right too. I just want to be a normal weight and healthy.

Good luck! We can do this!

Hello, I think perhaps if you reduced slower you would not get the side effects.  I reduced over 10 months, which sounds a long time, but it worked for me.  2 weeks on each dose is quite a short time.  I was on months on each dose, gradually reducing by cutting up generic Venlafaxine pills.  Try taking each dose for months rather thasn weeks, then cut pills to smaller and smaller doses until you are taking a tiny amount.  Reduce really slowly over months.  Hope you have managed to withdraw without too many side effects.  I took HRT for hot flushes.  I am in UK so do not have to pay for medication because of my age, but if you are in America I can understand that it will be costly for you to do as I did.   Let us know how you are