my dad has been put on baclofen 3 x 5mg daily. he had dementia and it obviously is too strong for him and knocked him off his feet. muscle so relaxed he struggling to eat talk smile how long does it take to come out system. he only a very slight build and struggling drink to flush it through cause he just asleep all the time on this medication.
We can assume it depends on his health system. Digestion times are personal.
The half life of Baclofen is 2 - 6 hours. Since the drug is eliminated from the body relatively quickly it is taken in several doses spread across the day.
In elderly patients a lowering of the daily dose might be required. It is best to talk to the physician who prescribed the drug.